METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE

METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE - Names and Identifiers

Name	chloro(diisopropylamino)methoxyphosphine
Synonyms	chloro(diisopropylamino)methoxyphosphine CHLORO(DIISOPROPYLAMINO)METHOXYPHOSPHINE METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE methyl N,N-diisopropylchlorophosphoramidite N,N-diisopropylmethylphosphonamidic chloride N,N-DIISOPROPYLMETHYLPHOSPHONAMIDIC CHLORIDE METHYL N,N-DIISOPROPYLPHOSPHORAMIDOCHLORIDITE methyl bis(1-methylethyl)amidochlorophosphite 1-chloro-N,N-diisopropyl-1-methoxyphosphanamine N,N-Diisopropylamidochloridophosphorous acid methyl ester Chloro(diisopropylamino)methoxyphosphine, Methyl N,N-diisopropylchlorophosphoramidite, Methyl N,N-diisopropylphosphoramidochloridite
CAS	86030-43-5
InChI	InChI=1/C7H17ClNOP/c1-6(2)9(7(3)4)11(8)10-5/h6-7H,1-5H3

METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE - Physico-chemical Properties

Molecular Formula	C7H17ClNOP
Molar Mass	197.64
Density	1.018 g/mL at 25 °C (lit.)
Boling Point	34-35 °C/0.8 mmHg (lit.)
Flash Point	163°F
Vapor Presure	0.375mmHg at 25°C
Appearance	liquid (turbid viscous)
Color	turbid, viscous
BRN	3600769
pKa	1.55±0.70(Predicted)
Storage Condition	Refrigerator
Refractive Index	n20/D 1.470

METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
FLUKA BRAND F CODES	10-21-23
Hazard Class	8
Packing Group	III

METHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE - Introduction

Chloro (diisopropylamino)methoxyphosphine is an organophosphorus compound with the formula [ClP(ON(i-Pr)2)2)2. It is a colorless or pale yellow liquid with a pungent odor.

Chloro (diisopropylamino)methoxyphosphine can be used as reagents and intermediates in organic synthesis. It is used in organometallic chemistry as a phosphine ligand for transition metal complexes. It can also be used to introduce phosphorus atoms in organic synthesis, participate in phosphating reactions and oxidation reactions.

Chloro (diisopropylamino)methoxyphosphine can be prepared by reacting methoxyphosphonic acid with thionyl chloride. The preparation method can also be prepared by reacting methyl chloride and diisopropylamine with sulfurous acid.

When using chloro(diisopropylamino)methoxyphosphine, pay attention to its safety information. It is an organic compound, so contact with skin and eyes should be avoided, and good ventilation conditions should be maintained. During the reaction, correct experimental procedures should be followed and appropriate protective equipment should be worn.

Last Update：2024-04-10 22:29:15