METHYL PROTOCATECHUATE
Methyl 3,4-dihydroxybenzoate
CAS: 2150-43-8
Molecular Formula: C8H8O4
METHYL PROTOCATECHUATE - Names and Identifiers
| Name | Methyl 3,4-dihydroxybenzoate |
| Synonyms | RARECHEM AL BF 0069 Methyl protocatechuate METHYL PROTOCATECHUATE METHYL PROTOCATECHUATE) METHYL 3,4-DIHYDROXYBENZOATE Methyl 3,4-dihydroxybenzoate 3,4-dihydroxy-2-methylbenzoate 3,4-Dihydroxybenzoic acid methyl ester 3,4-DIHYDROXY-BENZOIC ACID METHYL ESTER |
| CAS | 2150-43-8 |
| InChI | InChI=1/C8H8O4/c1-12-8(11)5-2-3-6(9)7(10)4-5/h2-4,9-10H,1H3 |
METHYL PROTOCATECHUATE - Physico-chemical Properties
| Molecular Formula | C8H8O4 |
| Molar Mass | 168.15 |
| Density | 1.354±0.06 g/cm3(Predicted) |
| Melting Point | 134-135°C |
| Boling Point | 120-180 °C(Press: 1.5 Torr) |
| Flash Point | 148.5°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 2.02E-05mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | White to Off-White |
| BRN | 1637939 |
| pKa | 8.19±0.18(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.587 |
| MDL | MFCD00016437 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Coptis chinensis. |
| In vitro study | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) alleviates the toxic effects of F - via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells. |
| In vivo study | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F - accumulation and oxidative stress. Methyl 3,4-dihydroxybenzoate prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2. |
METHYL PROTOCATECHUATE - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37 - Wear suitable gloves. |
| HS Code | 29182900 |
METHYL PROTOCATECHUATE - Reference
| Reference Show more | 1. [IF=4.167] Hu Ruizhi et al."Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets."J Anim Sci Biotechno. 2020 Dec;11(1):1-12 2. [IF=4.411] Yue Li et al.Impact of Drying Methods on Phenolic Components and Antioxidant Activity of Sea Buckthorn (Hippophae rhamnoides L.) Berries from Different Varieties in China.Molecules. 2021 Jan;26(23):7189 |
METHYL PROTOCATECHUATE - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| Biological activity | Methyl 3, 4-dioxybenzoate (Protocatechuic acid methyl ester) is the main metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effects. |
Last Update：2024-04-09 15:16:48
Supplier List
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple SpecificationsSpot supply
Product Name: Methyl 3,4-Dihydroxybenzoate Visit Supplier Webpage Request for quotationCAS: 2150-43-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Methyl 3,4-dihydroxybenzoate Request for quotationCAS: 2150-43-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple SpecificationsSpot supply
Product Name: Methyl 3,4-Dihydroxybenzoate Visit Supplier Webpage Request for quotationCAS: 2150-43-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History