Name | Methyl o-toluate |
Synonyms | Methyl o-toluate METHYL 2-TOLUATE METHYL O-TOLUATE RARECHEM AL BF 0047 2-METHYL METHYLBENZOATE methyl 2-methylbenzoate METHYL 2-METHYLBENZOATE METHYL-O-METHYL BENZOATE O-TOLUIC ACID METHYL ESTER o-Toluic Acid Methyl Ester 2-METHYLBENZOIC ACID METHYL ESTER |
CAS | 89-71-4 |
EINECS | 201-932-2 |
InChI | InChI=1/C9H10O2/c1-7-5-3-4-6-8(7)9(10)11-2/h3-6H,1-2H3 |
InChIKey | WVWZECQNFWFVFW-UHFFFAOYSA-N |
Molecular Formula | C9H10O2 |
Molar Mass | 150.17 |
Density | 1.073 g/mL at 25 °C (lit.) |
Melting Point | <-50 °C |
Boling Point | 207-208 °C (lit.) |
Flash Point | 82 °C |
Water Solubility | Not miscible or difficult to mix in water. |
Vapor Presure | 12.9Pa at 23℃ |
Appearance | Liquid |
Color | Clear colorless |
BRN | 2041846 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.518-1.52 |
MDL | MFCD00008428 |
Physical and Chemical Properties | Colorless liquid. |
Use | Used as a dye and pharmaceutical intermediates |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29163990 |
Hazard Class | IRRITANT |
LogP | 3 at 25℃ |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Application | methyl O-toluate can be widely used as a pharmaceutical synthesis intermediate, such as the synthesis of doxepin hydrochloride. Doxepin hydrochloride is used in the treatment of depression and Anxiety neurosis drugs, its role is to inhibit the central nervous system for serotonin and norepinephrine reuptake, as a result, the concentrations of these two neurotransmitters in the synaptic cleft are increased to exert an antidepressant effect, and also have an anti-Anxiety and sedative effect. |
Use | organic synthesis intermediates. used as dye and pharmaceutical intermediate |