MG 310

MG 310 - Names and Identifiers

Name	2-N-Boc-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
Synonyms	MG 310 2-Boc-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid N-Boc-1,2,3,4-Tetrahydro-isoquinoline-1-carboxylic acid 2-N-BOC-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID 2-N-Boc-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 3,4-Dihydro-1,2(1H)-isoquinolinedicarboxylic acid 2-(1,1-dimethylethyl) ester 1,2(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(1,1-dimethylethyl) ester
CAS	166591-85-1
InChI	InChI=1/C15H19NO4/c1-15(2,3)20-14(19)16-9-8-10-6-4-5-7-11(10)12(16)13(17)18/h4-7,12H,8-9H2,1-3H3,(H,17,18)

MG 310 - Physico-chemical Properties

Molecular Formula	C15H19NO4
Molar Mass	277.32
Density	1.222±0.06 g/cm3(Predicted)
Boling Point	436.7±45.0 °C(Predicted)
Flash Point	217.9°C
Vapor Presure	2.12E-08mmHg at 25°C
pKa	3.49±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.556

MG 310 - Introduction

2-N-Boc-1,2,3, Acid (Boc-Tetrahydroisoquinoline-1-Carboxylic Acid for short) is an organic compound whose chemical formula is C16H23NO3.

Nature:
1. Appearance: Boc-Tetrahydroisoquinoline-1-Carboxylic Acid is a white crystalline solid.
2. Melting Point: about 110-113 ℃.
3. Solubility: It is soluble in some organic solvents such as ethanol, dimethylformamide and dichloromethane, but it is difficult to dissolve in water.

Use:
Boc-Tetrahydroisoquinoline-1-Carboxylic Acid is commonly used in organic synthesis, the main uses are as follows:
1. Is a commonly used protecting group, can protect the amine group.
2. It can be used as an intermediate in synthesis research, especially in the field of synthesis of biologically active molecules.

Method:
The preparation of Boc-Tetrahydroisoquinoline-1-Carboxylic Acid can be carried out by the following steps:
1. The N-Boc-protected tetrahydroisoquinoline is reacted with formic acid under alkaline conditions.
2. In a suitable solvent environment, the reaction solution is treated with dilute acid to crystallize the resulting product.
3. The pure product was obtained by filtration and washing, and finally dried.

Safety Information:
Regarding the safety of Boc-Tetrahydroisoquinoline-1-Carboxylic Acid, in general, the following points need to be paid attention:
1. This compound may be irritating to the skin, eyes and respiratory tract, and should be used with appropriate protective measures, such as gloves, goggles and masks.
2. Avoid inhalation of dust and skin contact, avoid swallowing.
3. In the use and storage process, need to maintain good ventilation.
4. If the substance is accidentally touched, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15