Name | Mefloquine hydrochloride |
Synonyms | wr14249 s*)-(r(+-)-lorid Mefloquin hydrochloride Mefloquine hydrochloride MEFLOQUINE HYDROCHLORIDE (POLYMORPH FORM E) 2,8-bis(trifluoromethyl)-alpha-2-piperidinyl-4-quinolinemethanomonohydroch dl-erythro-alpha-(2-piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol (R)-[2,8-Bis(trifluoromethyl)-4-quinolyl]-[(2S)-2-piperidyl]methanol hydrochloride |
CAS | 51773-92-3 |
EINECS | 257-412-0 |
InChI | InChI=1/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H |
InChIKey | WESWYMRNZNDGBX-YLCXCWDSSA-N |
Molecular Formula | C17H17ClF6N2O |
Molar Mass | 414.77 |
Melting Point | 250-254?C |
Boling Point | 415.7°C at 760 mmHg |
Flash Point | 205.2°C |
Solubility | DMSO: 38mg/mL, soluble |
Vapor Presure | 1.18E-07mmHg at 25°C |
Appearance | solid |
Color | white |
Maximum wavelength(λmax) | ['222nm(Acidic H2O)(lit.)'] |
Merck | 14,5801 |
Storage Condition | 2-8°C |
Stability | Temperature Sensitive |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | VC0308000 |
HS Code | 2933399090 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.411 ml | 12.055 ml | 24.11 ml |
5 mM | 0.482 ml | 2.411 ml | 4.822 ml |
10 mM | 0.241 ml | 1.205 ml | 2.411 ml |
5 mM | 0.048 ml | 0.241 ml | 0.482 ml |
Biological activity | Mefloquine HCl is a blood schizoncide that inhibits the formation of plasmodium pigment and is used as an anti-malarial drug. |