Methyl 3-bromo-2-chloropyridine-5-carboxylate

Methyl 3-bromo-2-chloropyridine-5-carboxylate - Names and Identifiers

Name	Methyl 5-bromo-6-chloropyridine-3-carboxylate
Synonyms	Methyl 5-bromo-6-chl METHYL 5-BROMO-6-CHLORONICOTINATE Methyl 5-bromo-6-chloronicotinate 5-BROMO-6-CHLORONICOTINIC ACID METHYL ESTER methyl 5-bromo-6-chloropyridine-3-carboxylate Methyl 5-bromo-6-chloropyridine-3-carboxylate Methyl 3-bromo-2-chloropyridine-5-carboxylate 3-Pyridinecarboxylic acid, 5-bromo-6-chloro-, methyl ester Methyl 5-bromo-6-chloropyridine-3-carboxylate, Methyl 3-bromo-2-chloropyridine-5-carboxylate
CAS	78686-77-8
InChI	InChI=1/C7H5BrClNO2/c1-12-7(11)4-2-5(8)6(9)10-3-4/h2-3H,1H3
InChIKey	WINGWVOUOFMOJQ-UHFFFAOYSA-N

Methyl 3-bromo-2-chloropyridine-5-carboxylate - Physico-chemical Properties

Molecular Formula	C7H5BrClNO2
Molar Mass	250.48
Density	1.684
Melting Point	75-77°C
Boling Point	279.2±35.0 °C(Predicted)
Flash Point	122.7°C
Solubility	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Vapor Presure	0.00407mmHg at 25°C
Appearance	White solid
Color	White to Off-White
pKa	-2.84±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.568
MDL	MFCD03844855

Methyl 3-bromo-2-chloropyridine-5-carboxylate - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Class	IRRITANT

Methyl 3-bromo-2-chloropyridine-5-carboxylate - Introduction

Methyl is an organic compound with the chemical formula C7H4BrClNO2. The following are some properties, uses, preparation and safety information about the compound:

Nature:
-Appearance: Colorless to Su-yellow solid
-Melting point: about 70-74 ℃
-Boiling point: about 280 ℃
-Density: 1.66g/cm3
-Solubility: Slightly soluble in water, soluble in some organic solvents

Use:
- Methyl is an important intermediate compound in organic synthesis. It can be used to synthesize various compounds containing nicotinic acid structure, such as drugs, pesticides and dyes.

Preparation Method:
- Methyl is usually prepared by acylation of nicotinic acid (pyridine-3-carboxylic acid). Specific reaction conditions can be optimized according to specific laboratory conditions and requirements.

Safety Information:
- Methyl is an organic compound and should be used in accordance with routine laboratory safety procedures.
-The compound may be irritating and may cause eye and skin irritation. Contact with skin and eyes should be avoided.
-When handling or handling the compound, take appropriate personal protective measures, such as wearing protective gloves, eye protection equipment and protective clothing.
-Please use in a well-ventilated place and avoid inhaling its vapor.

Last Update：2024-04-09 02:00:48