Methyl (R)-(+)-3-(tert-butyldimethylsilyloxy)-5-oxo-1-cyclopentene-1-heptanoate - Names and Identifiers
Name | methyl (R)-(+)-3-(T-bu-dimethylsilyloxy)-5-oxo-1-
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Synonyms | methyl (R)-(+)-3-(T-bu-dimethylsilyloxy)-5-oxo-1- METHYL-7-(3-(R)-T-BUTYL DIMETHYLSILOXY-5-OXO-CYCLOPENT-1-ENYL)-HEPTANOATE METHYL (R)-(+)-3-(TERT-BUTYLDIMETHYLSILYLOXY)-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE Methyl (R)-(+)-3-(tert-butyldimethylsilyloxy)-5-oxo-1-cyclopentene-1-heptanoate (R)-Methyl 7-(3-((Tert-Butyldimethylsilyl)Oxy)-5-Oxcyclopent-1-En-1-Yl)Heptanoate (R)-Methyl 7-(3-((tert-butyldimethylsilyl)-oxy)-5-oxocyclopent-1-en-1-yl)heptanoate methyl 7-[(3R)-3-{[tert-butyl(dimethyl)silyl]oxy}-5-oxocyclopent-1-en-1-yl]heptanoate 7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester 1-Cyclopentene-1-heptanoic acid,3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo,methyl ester,(3R)- 1-Cyclopentene-1-heptanoic acid,3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-oxo-, methyl ester, (3R)-
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CAS | 41138-69-6
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InChI | InChI=1/C19H34O4Si/c1-19(2,3)24(5,6)23-16-13-15(17(20)14-16)11-9-7-8-10-12-18(21)22-4/h13,16H,7-12,14H2,1-6H3/t16-/m0/s1 |
Methyl (R)-(+)-3-(tert-butyldimethylsilyloxy)-5-oxo-1-cyclopentene-1-heptanoate - Physico-chemical Properties
Molecular Formula | C19H34O4Si
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Molar Mass | 354.56 |
Density | 0.977g/mLat 25°C(lit.) |
Boling Point | 210°C(lit.) |
Flash Point | 41°C |
Vapor Presure | 8.89E-07mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.467(lit.) |
Methyl (R)-(+)-3-(tert-butyldimethylsilyloxy)-5-oxo-1-cyclopentene-1-heptanoate - Risk and Safety
Risk Codes | 10 - Flammable
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Safety Description | 16 - Keep away from sources of ignition.
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UN IDs | UN 3272 3/PG 3 |
Methyl (R)-(+)-3-(tert-butyldimethylsilyloxy)-5-oxo-1-cyclopentene-1-heptanoate - Introduction
methyl (R)-( )-3-(T-bu-dimethylsilyloxy)-5-oxo-1-is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of the compound:
Nature:
-Chemical formula: C16H30O3Si
-Molecular weight: 298.49g/mol
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents
Use:
methyl (R)-( )-3-(T-bu-dimethylsilyloxy)-5-oxo-1-is often used as a reagent in organic synthesis for the synthesis of other organic compounds. It can be used as an intermediate in chiral synthesis for the synthesis of pharmacologically active compounds or for the preparation of chiral catalysts.
Preparation Method:
The preparation of methyl (R)-( )-3-(T-bu-dimethylsilyloxy)-5-oxo-1-can be carried out by the following steps:
1. The heptenoic acid methyl ester reacts with 1,1-dimethylethyl lithium to generate a lithium salt.
2. The lithium salt is reacted with (3R)-3-[[(1,1-dimethylethyl) dimethylsilyl] oxy]-5-oxo-cyclopent-1-ene to generate the target product.
Safety Information:
The use of organic compounds should follow the appropriate safety procedures. This compound may be irritating and volatile, and contact with skin and eyes should be avoided. Wear chemical protective gloves and goggles during operation. If necessary, it should be operated under well-ventilated conditions. If taken by mistake or inhaled by mistake, seek medical attention immediately.
Last Update:2024-04-10 22:29:15