Methyl 2-chloro-3-fluoroisonicotinate

Methyl 2-chloro-3-fluoroisonicotinate - Names and Identifiers

Name	4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester
Synonyms	Methyl 2-Chloro-3-fluoroisonicotinate Methyl 2-chloro-3-fluoroisonicotinate Methyl-2-chlor-3-fluorpyridin-4-carboxylat methyl 2-chloro-3-fluoropyridine-4-carboxylate 2-Chloro-3-fluoroisonicotinic acid methyl ester 2-Chloro-3-fluoro-4-pyridinecarboxylic acid methyl ester 4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester 4-pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester
CAS	628691-95-2
InChI	InChI=1/C7H5ClFNO2/c1-12-7(11)4-2-3-10-6(8)5(4)9/h2-3H,1H3

Methyl 2-chloro-3-fluoroisonicotinate - Physico-chemical Properties

Molecular Formula	C7H5ClFNO2
Molar Mass	189.57
Density	1.386
Boling Point	258℃
Flash Point	110℃
Vapor Presure	0.0145mmHg at 25°C
pKa	-1.34±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.511

Methyl 2-chloro-3-fluoroisonicotinate - Introduction

4-Pyridinecarboxylic acid, 2-choro-3-fluoro-, methyl ester is an organic compound with the chemical formula C≡H≡ClFNO₂. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-Pyridinecarboxylic acid, 2-choro-3-fluoro-, methyl ester is a colorless to yellowish liquid.
-Solubility: It is soluble in organic solvents such as ethanol, methanol and dichloromethane, but insoluble in water.

Use:
- 4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester can be used as a reagent in organic synthesis and used in the synthesis of other organic compounds.
-Because it contains pyridine ring and ester group, it can also be used as an intermediate for pyridine compounds.

Preparation Method:
- 4-Pyridinecarboxylic acid, 2-chloro-3-fluoro-, methyl ester is generally prepared by chemical reaction. One such method is the reaction of 2-chloro-3-fluoropyridine-4-carboxylic acid with methyl formate to produce the desired product.

Safety Information:
- 4-Pyridinecarboxylic acid, 2-choro-3-fluoro-, methyl ester should be careful to prevent contact with fire and oxygen during storage and operation to avoid explosion.
-Use with appropriate protective equipment, such as goggles and gloves, to avoid contact with the skin.
-Pay attention to good ventilation during operation to prevent inhalation of its vapor.
-If inhaled or in contact with skin, eyes or ingestion, seek medical help immediately and provide information on the chemical.

Last Update：2024-04-10 22:29:15