Methyl 2-hydroxynicotinate
Methyl 2-hydroxynicotinate
CAS: 67383-31-7
Molecular Formula: C7H7NO3
Methyl 2-hydroxynicotinate - Names and Identifiers
Methyl 2-hydroxynicotinate - Physico-chemical Properties
| Molecular Formula | C7H7NO3 |
| Molar Mass | 153.14 |
| Density | 1.287 |
| Boling Point | 287 °C |
| Flash Point | 127 °C |
| pKa | 8.56±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
Methyl 2-hydroxynicotinate - Introduction
Methyl 2-hydroxynicotinate is an organic compound with a chemical formula of C7H7NO3 and a molecular weight of 153.14g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Methyl 2-hydroxyynicotinate is a colorless to yellow crystal or crystalline powder.
-Solubility: its solubility in water is low, more soluble in ethanol, chloroform and ether solvents.
Use:
-Pharmaceutical field: Methyl 2-hydroxynicotinate is commonly used in the preparation of pharmaceutical intermediates, especially drugs against cardiovascular diseases.
-Cosmetics field: The compound can also be used in skin care products and cosmetics, with antioxidant and anti-inflammatory effects.
Preparation Method:
Methyl 2-hydroxynicotinate can be synthesized by the following steps:
1. Reaction of nicotinic acid with methanol to obtain dimethyl formate and hydroxynicotinic acid under the action of a catalyst.
2. Continue the reaction to allow dimethyl formate to react with hydroxynicotinic acid to synthesize Methyl 2-hydroxynicotinate.
Safety Information:
- Methyl 2-hydroxynicotinate may be irritating and should be rinsed immediately with plenty of water if it enters the eyes or skin.
-Avoid inhaling the dust or vapor of the compound during operation, and wear suitable protective equipment, such as respirators and gloves.
-The compound should be stored in a closed container and avoid contact with oxidants and high temperatures to prevent unpredictable reactions.
- Methyl 2-hydroxyynicotinate is a chemical. Please read carefully and follow relevant safety operation guidelines and technical specifications before use.
Nature:
-Appearance: Methyl 2-hydroxyynicotinate is a colorless to yellow crystal or crystalline powder.
-Solubility: its solubility in water is low, more soluble in ethanol, chloroform and ether solvents.
Use:
-Pharmaceutical field: Methyl 2-hydroxynicotinate is commonly used in the preparation of pharmaceutical intermediates, especially drugs against cardiovascular diseases.
-Cosmetics field: The compound can also be used in skin care products and cosmetics, with antioxidant and anti-inflammatory effects.
Preparation Method:
Methyl 2-hydroxynicotinate can be synthesized by the following steps:
1. Reaction of nicotinic acid with methanol to obtain dimethyl formate and hydroxynicotinic acid under the action of a catalyst.
2. Continue the reaction to allow dimethyl formate to react with hydroxynicotinic acid to synthesize Methyl 2-hydroxynicotinate.
Safety Information:
- Methyl 2-hydroxynicotinate may be irritating and should be rinsed immediately with plenty of water if it enters the eyes or skin.
-Avoid inhaling the dust or vapor of the compound during operation, and wear suitable protective equipment, such as respirators and gloves.
-The compound should be stored in a closed container and avoid contact with oxidants and high temperatures to prevent unpredictable reactions.
- Methyl 2-hydroxyynicotinate is a chemical. Please read carefully and follow relevant safety operation guidelines and technical specifications before use.
Last Update：2024-04-09 02:00:47
