Methyl 4-(hydroxyMethyl)picolinate

Methyl 4-(hydroxyMethyl)picolinate - Names and Identifiers

Name	Methyl 4-(hydroxymethyl)pyridine-2-carboxylate
Synonyms	Methyl 4-(hydroxymethyl)pyridi Methyl 4-(hydroxyMethyl)picolinate Methyl 4-(hydroxymethyl)pyridine-2-carboxylate 4-hydroxymethylpyridin-2-carboxylic acid methyl ester 4-Hydroxymethyl-pyridine-2-carboxylic acid methyl ester 2-Pyridinecarboxylicacid,4-(Hydroxymethyl)-,Methylester 4-(hydroxymethyl)-2-Pyridinecarboxylic acid methyl ester 2-pyridinecarboxylic acid, 4-(hydroxymethyl)-, methyl ester 2-Pyridinecarboxylic acid, 4-(hydroxymethyl)-, methyl ester 2-Pyridinecarboxylicacid,4-(hydroxymethyl)-,methylester(9CI)
CAS	317335-15-2
InChI	InChI=1/C8H9NO3/c1-12-8(11)7-4-6(5-10)2-3-9-7/h2-4,10H,5H2,1H3

Methyl 4-(hydroxyMethyl)picolinate - Physico-chemical Properties

Molecular Formula	C8H9NO3
Molar Mass	167.16
Density	1.244±0.06 g/cm3(Predicted)
Melting Point	74-76℃
Boling Point	335.8±32.0 °C(Predicted)
Flash Point	156.9°C
Vapor Presure	4.61E-05mmHg at 25°C
pKa	13.17±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.546

Methyl 4-(hydroxyMethyl)picolinate - Introduction

Methyl 4-(pyridine-2-carboxylate) (Methyl 4-(hydroxymethyl)pyridine-2-carboxylate) is an organic compound with the molecular formula C8H9NO3.

Nature:
1. Appearance: colorless liquid or solid
2. Melting Point: 60-64 ° C
3. Boiling Point: 259-261 ° C
4. Solubility: soluble in some organic solvents, such as alcohol and ether, slightly soluble in water.

Use:
Methyl 4-(hydroxymethyl)pyridine-2-carboxylate is widely used in the field of organic synthesis and is an important intermediate for the synthesis of drugs, pesticides and materials. It can be used as an intermediate in the synthesis of drugs in the pharmaceutical field, with analgesic, anti-inflammatory and antioxidant activities. In addition, it can also be used in the research fields of biotechnology and materials science.

Method:
The preparation of Methyl 4-(hydroxymethyl)pyridine-2-carboxylate is usually obtained by reacting 2-pyridyl methanol with a chloroformate. The specific step is that 2-pyridylmethanol and chloroformate are esterified in the presence of sodium carbonate, and then appropriately purified to obtain the target product.

Safety Information:
The safety evaluation of Methyl 4-(hydroxymethyl)pyridine-2-carboxylate is limited, and appropriate laboratory practices and standard operating procedures need to be followed during use, storage and disposal. It may cause irritation to the human body, so contact with the skin, eyes and respiratory tract should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during use. Always comply with local regulations and safety guidelines and ensure that the substance is used and stored under safe conditions.

Last Update：2024-04-09 20:52:54