Methyl 4-hydroxypiperidine-1-carboxylate
Methyl 4-hydroxypiperidine-1-carboxyl
CAS: 75250-52-1
Molecular Formula: C7H13NO3
Methyl 4-hydroxypiperidine-1-carboxylate - Names and Identifiers
| Name | Methyl 4-hydroxypiperidine-1-carboxyl |
| Synonyms | Methyl 4-hydroxypiperidine-1-carboxyl Methyl 4-hydroxypiperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-hydroxy-, methyl ester |
| CAS | 75250-52-1 |
Methyl 4-hydroxypiperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C7H13NO3 |
| Molar Mass | 159.19 |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD12181166 |
Methyl 4-hydroxypiperidine-1-carboxylate - Upstream Downstream Industry
| Raw Materials | 1(2H)-Pyridinecarboxylicacid,3,6-dihydro-,methylester(9CI) methyl 4-oxopiperidine-1-carboxylate 1,2,3,6-TETRAHYDROPYRIDINE 4-Hydroxypiperidine 4-Piperidinone Methyl chloroformate |
Methyl 4-hydroxypiperidine-1-carboxylate - Introduction
Methyl 4-hydroxypiperidine-1-carboxylate, chemical formula C8H15NO3, is an organic compound.
Nature:
-Appearance: Usually colorless or yellowish liquid.
-Molecular weight: 173.21g/mol.
-Solubility: Soluble in water and common organic solvents, such as alcohols and ethers.
-Melting point: About -9 ° C.
-Boiling point: About 220 ° C.
-Density: about 1.06 g/mL.
Use:
-Methyl 4-hydroxypiperidine-1-carboxylate is often used as an intermediate in the synthesis of drugs and pesticides.
-In the field of organic synthesis, it can be used as a raw material for the preparation of piperidone, kasidone, picodone and other compounds.
Method:
Methyl 4-hydroxypiperidine-1-carboxylate can be synthesized by the following steps:
1. First, reacting 4-hydroxypiperidine with methanol to obtain 4-hydroxypiperidine-1-methanol;
2. Next, 4-hydroxypiperidine-1-methanol is reacted with formic acid to produce methyl 4-hydroxypiperidine-1-carboxylate.
Safety Information:
The specific toxicity and harmfulness of methyl 4-hydroxypiperidine-1-carboxylic acid ester has not been extensively studied, so it is necessary to follow safe operating procedures when used. If the experiment is carried out, it should be equipped with appropriate personal protective equipment to avoid inhalation, contact with skin and eyes. In addition, try to keep its packaging intact and store it in a cool, dry and well-ventilated place. If the compound is inhaled, exposed, or ingested, immediate medical attention and information should be obtained.
Nature:
-Appearance: Usually colorless or yellowish liquid.
-Molecular weight: 173.21g/mol.
-Solubility: Soluble in water and common organic solvents, such as alcohols and ethers.
-Melting point: About -9 ° C.
-Boiling point: About 220 ° C.
-Density: about 1.06 g/mL.
Use:
-Methyl 4-hydroxypiperidine-1-carboxylate is often used as an intermediate in the synthesis of drugs and pesticides.
-In the field of organic synthesis, it can be used as a raw material for the preparation of piperidone, kasidone, picodone and other compounds.
Method:
Methyl 4-hydroxypiperidine-1-carboxylate can be synthesized by the following steps:
1. First, reacting 4-hydroxypiperidine with methanol to obtain 4-hydroxypiperidine-1-methanol;
2. Next, 4-hydroxypiperidine-1-methanol is reacted with formic acid to produce methyl 4-hydroxypiperidine-1-carboxylate.
Safety Information:
The specific toxicity and harmfulness of methyl 4-hydroxypiperidine-1-carboxylic acid ester has not been extensively studied, so it is necessary to follow safe operating procedures when used. If the experiment is carried out, it should be equipped with appropriate personal protective equipment to avoid inhalation, contact with skin and eyes. In addition, try to keep its packaging intact and store it in a cool, dry and well-ventilated place. If the compound is inhaled, exposed, or ingested, immediate medical attention and information should be obtained.
Last Update：2024-04-09 21:01:54
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Raw Materials for Methyl 4-hydroxypiperidine-1-carboxylate
1(2H)-Pyridinecarboxylicacid,3,6-dihydro-,methylester(9CI)
methyl 4-oxopiperidine-1-carboxylate
1,2,3,6-TETRAHYDROPYRIDINE
4-Hydroxypiperidine
4-Piperidinone
Methyl chloroformate
methyl 4-oxopiperidine-1-carboxylate
1,2,3,6-TETRAHYDROPYRIDINE
4-Hydroxypiperidine
4-Piperidinone
Methyl chloroformate