Methyl 5-bromoindole-2-carboxyate

Methyl 5-bromoindole-2-carboxyate - Names and Identifiers

Name	Methyl 5-bromo-1H-indole-2-carboxylate
Synonyms	ZINC00499439 Methyl 5-bromoindole-2-carboxyate Methyl 5-bromo-1H-indole-2-carboxylate 5-Bromoindole-2-carboxylic acid methyl ester 5-BROMOINDOLE-2-CARBOXYLIC ACID METHYL ESTER 1H-Indole-2-carboxylic acid, 5-broMo-, Methyl ester 1H-Indole-2-carboxylic acid, 5-bromo-, methyl ester
CAS	210345-56-5
InChI	InChI=1/C10H8BrNO2/c1-14-10(13)9-5-6-4-7(11)2-3-8(6)12-9/h2-5,12H,1H3

Methyl 5-bromoindole-2-carboxyate - Physico-chemical Properties

Molecular Formula	C10H8BrNO2
Molar Mass	254.08
Density	1.629±0.06 g/cm3(Predicted)
Melting Point	211.8-213.6 °C(Solv: toluene (108-88-3))
Boling Point	386.2±22.0 °C(Predicted)
Flash Point	187.3°C
Vapor Presure	3.61E-06mmHg at 25°C
pKa	14.01±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.666

Methyl 5-bromoindole-2-carboxyate - Introduction

Methyl is an organic compound with the chemical formula C10H8BrNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Methyl is a colorless to pale yellow liquid.
-Melting point: About -4 ℃.
-Boiling point: About 278-280 ℃.
-Density: About 1.47g/cm³.
-Solubility: Soluble in ethanol and Ether solvents.

Use:
- Methyl L can be used as an intermediate in organic synthesis.
-It is often used in the pharmaceutical field to synthesize certain pharmaceutical compounds.

Method:
The preparation of-methyll can be prepared by the reaction of indole and hydrobromic acid.
-The specific synthesis steps are as follows: first, indole and hydrobromic acid are reacted in an organic solvent to generate 5-bromoindole, and then reacted with methyl formate to generate the target product.

Safety Information:
- Methyl L is an organic mixture that may cause certain health hazards.
-Wear appropriate personal protective equipment such as safety glasses, gloves, etc.
-Avoid contact with skin, eyes and respiratory tract to avoid irritation or injury.
-Keep away from fire or heat sources during use and storage to prevent fire and explosion.
-Observe safe operating procedures when using, and ensure that the operation is carried out in a well-ventilated place.

Last Update：2024-04-09 02:00:44