Name | Methyl bromopyruvate |
Synonyms | BrCH2COCO2Me METHYL BROMOPYRUVATE Methyl bromopyruvate Methyl broMide acetone Methyl 3-bromo-2-oxopropanoate METHYL 3-BROMO-2-OXOPROPANOATE Methyl broMopyruvate technical 3-bromo-2-oxoPropanoic acid methyl ester 3-Bromo-2-oxopropionic acid methyl ester Propanoic acid, 3-bromo-2-oxo-, methyl ester Methyl bromopyruvate, Methyl 3-bromo-2-oxopropionate |
CAS | 7425-63-0 |
InChI | InChI=1/C4H5BrO3/c1-8-4(7)3(6)2-5/h2H2,1H3 |
InChIKey | MQONVZMIFQQQHA-UHFFFAOYSA-N |
Molecular Formula | C4H5BrO3 |
Molar Mass | 180.98 |
Density | 1.70 g/mL at 20 °C (lit.) |
Melting Point | 5°C(lit.) |
Boling Point | 84°C/10mmHg(lit.) |
Flash Point | 125°C |
Vapor Presure | 0.65mmHg at 25°C |
Appearance | clear liquid |
Color | Light orange to Yellow to Green |
BRN | 1754888 |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.480 |
Physical and Chemical Properties | This product B. p.82 ~ 84 ℃/133 Mpa,n20D 1.463, relative density of 1.70, soluble in organic solvents. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
UN IDs | UN 3334 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 19 |
Use | methyl 3-bromopyruvate is an intermediate of the fungicide thiabendazole. used as pharmaceutical intermediates, medicinal raw materials |
production method | the preparation method is to slowly add bromine Dropwise to the solution of methyl pyruvate and its solvent at 65 ℃, and continuous stirring, dropping time to be greater than 45min, 3-bromopyruvate methyl ester, after the post-treatment product. Methyl 3-bromopyruvate can also be produced by esterification of 3-bromopyruvate with methanol in the presence of a catalyst. |