Methyl trifluoromethanesulfate
methyl trifluoromethanesulphonate
CAS: 333-27-7
Molecular Formula: C2H3F3O3S
Methyl trifluoromethanesulfate - Names and Identifiers
Methyl trifluoromethanesulfate - Physico-chemical Properties
| Molecular Formula | C2H3F3O3S |
| Molar Mass | 164.1 |
| Density | 1.45g/mLat 25°C(lit.) |
| Boling Point | 94-99°C(lit.) |
| Flash Point | 101°F |
| Vapor Presure | 49.662mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.450 |
| Color | Clear colorless to yellow |
| BRN | 774772 |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.326(lit.) |
| Physical and Chemical Properties | Boiling point 94-99°C(lit.) density 1.45g/mL at 25°C(lit.) refractive index n20/D 1.326(lit.) flash point 101 °F storage conditions 0-6°C |
Methyl trifluoromethanesulfate - Risk and Safety
| Risk Codes | R10 - Flammable R34 - Causes burns R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S16 - Keep away from sources of ignition. |
| UN IDs | UN 2920 8/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| TSCA | T |
| HS Code | 29049020 |
| Hazard Note | Highly Toxic/Corrosive |
| Hazard Class | 3.2 |
| Packing Group | III |
Methyl trifluoromethanesulfate - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Overview | Methyl trifluoromethanesulfonate is a very useful class of trifluoromethanesulfonate reagents in organic synthesis, commonly used as alkylation reagents. The strong electron-withdrawing ability and reactivity of trifluoromethanesulfonyl groups of trifluoromethanesulfonate compounds are much higher than those of conventional alkylating reagents, such as chlorides or alkyl sulfonates. Because these compounds are very active, only methyl trifluoromethanesulfonate is relatively stable. Other trifluoromethanesulfonate is prone to side reactions such as elimination and rearrangement, which need to be combined and post-treated under mild conditions. |
| preparation | synthesis of methyl trifluoromethanesulfonate: under ice bath, trimethyl orthoformate (3.18g,30mmol) is slowly added to trifluoromethanesulfonate anhydride (8.47g,30mmol), transferred to 25 ℃ for reaction, nuclear magnetic resonance monitoring for 15 minutes, after reaction, 9.74g of colorless liquid of methyl trifluoromethanesulfonate is obtained by distillation under reduced pressure, with a yield of 99%. |
| Preparation method of methyl trifluoromethanesulfonate | Trifluoromethanesulfonic acid and potassium carbonate first form a salt, and react with dimethyl sulfate in DMF or DMSO, Then add water to wash and distill, or trifluoromethanesulfonic acid and methanol directly esterify. |
| uses | intermediates in organic synthesis and pharmaceutical synthesis, monomethylation reagents. |
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: methyl trifluoromethanesulphonate Request for quotation
CAS: 333-27-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 333-27-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: Methyl trifluoromethanesulfonate Request for quotationCAS: 333-27-7
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Methyl Trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Methyl trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Methyl trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Methyl trifluoromethanesulfonate Request for quotation
CAS: 333-27-7
Tel:
Email: peilingchem@sina.com
Mobile: 13127581762
QQ: 1736947057
Send QQ message
CAS: 333-27-7
Tel:
Email: peilingchem@sina.com
Mobile: 13127581762
QQ: 1736947057
Product Name: methyl trifluoromethanesulphonate Request for quotation
CAS: 333-27-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 333-27-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: methyl trifluoromethanesulphonate Request for quotationCAS: 333-27-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: Methyl trifluoromethanesulfonate Request for quotationCAS: 333-27-7
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Methyl Trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Methyl trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Methyl trifluoromethanesulfonate Visit Supplier Webpage Request for quotationCAS: 333-27-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Methyl trifluoromethanesulfonate Request for quotation
CAS: 333-27-7
Tel:
Email: peilingchem@sina.com
Mobile: 13127581762
QQ: 1736947057Send QQ message
CAS: 333-27-7
Tel:
Email: peilingchem@sina.com
Mobile: 13127581762
QQ: 1736947057
View History
Methyl trifluoromethanesulfate
TEGdiacrylate
4-Hydroxy-3-methoxybenzoic acid 3,7-dimethyl-5-oxo-2,6-octadienyl ester
TEGdiacrylate
4-Hydroxy-3-methoxybenzoic acid 3,7-dimethyl-5-oxo-2,6-octadienyl ester