Nα-Fmoc-Nω-tosyl-L-arginine
N(alpha)-fmoc-N(omega)-tosyl-L-arginine
CAS: 83792-47-6
Molecular Formula: C28H30N4O6S
Nα-Fmoc-Nω-tosyl-L-arginine - Names and Identifiers
| Name | N(alpha)-fmoc-N(omega)-tosyl-L-arginine |
| Synonyms | Fmoc-Arq(Tos)-OH Fmoc-Arg(Tos)-OH Fmoc-Arg(tos)-OH FMOC-NG-TOSYL-ARG-OH Na-Fmoc-Nw-Tos-L-arginine N-Fmoc-N'-tosyl-L-arginine Nα-Fmoc-Nω-tosyl-L-arginine N-FMOC-N-t-tosyl-L-arginine na-fmoc-N-omega-tosyl-L-arginine FMOC-NG-TOSYL-L-ARGININE ETHERATE N(alpha)-fmoc-N(omega)-tosyl-L-arginine Nalpha-fluorenylmethoxycarbonyl-Nomega-tosyl-L-arginine NALPHA-9-Fluorenylmethoxycarbonyl-NOMEGA-tosyl-L-arginine etherate (E)-N~5~-(amino{[(4-methylphenyl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine (E)-N~5~-(amino{[(4-methylphenyl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine |
| CAS | 83792-47-6 |
| InChI | InChI=1/C28H30N4O6S/c1-18-12-14-19(15-13-18)39(36,37)32-27(29)30-16-6-11-25(26(33)34)31-28(35)38-17-24-22-9-4-2-7-20(22)21-8-3-5-10-23(21)24/h2-5,7-10,12-15,24-25H,6,11,16-17H2,1H3,(H,31,35)(H,33,34)(H3,29,30,32)/t25-/m1/s1 |
Nα-Fmoc-Nω-tosyl-L-arginine - Physico-chemical Properties
| Molecular Formula | C28H30N4O6S |
| Molar Mass | 550.63 |
| Density | 1.38±0.1 g/cm3(Predicted) |
| Melting Point | ~80°C (dec.) |
| Appearance | Powder |
| Color | White |
| pKa | 3.83±0.21(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.656 |
| MDL | MFCD00063331 |
Nα-Fmoc-Nω-tosyl-L-arginine - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29350090 |
| Hazard Class | IRRITANT |
Nα-Fmoc-Nω-tosyl-L-arginine - Introduction
N(alpha)-fmoc-N(omega)-tosyl-L-arginine is an organic compound whose chemical formula is C37H38N4O6S. It is an arginine derivative with a protecting group and is commonly used in chemical synthesis. The following is a brief description of its nature, use, preparation and safety information:
Properties: N(alpha)-fmoc-N(omega)-tosyl-L-arginine is a white crystalline solid. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane at room temperature, and has good stability.
Purpose: N(alpha)-fmoc-N(omega)-tosyl-L-arginine is a commonly used amino acid protecting group, which can be used in peptide synthesis and protein engineering. It can protect the amino group of arginine from reaction with other reactants, so as to realize selective synthesis and modification.
Preparation Method: In general, the synthesis of N(alpha)-fmoc-N(omega)-tosyl-L-arginine is carried out by first reacting with fluorenol to produce N(alpha)-fmoc-N(omega)-tosyl-L-arginine fluorenylmethyl ester, followed by acid hydrolysis to obtain the target product. This synthetic route requires certain operational skills and laboratory equipment.
Safety Information: For specific safety information about N(alpha)-fmoc-N(omega)-tosyl-L-arginine, please read the Safety Data Sheet (SDS) for the relevant chemical. When using and handling, please follow the laboratory's safe operating procedures, wear appropriate protective equipment, and ensure that the operation is carried out under well-ventilated conditions.
Properties: N(alpha)-fmoc-N(omega)-tosyl-L-arginine is a white crystalline solid. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane at room temperature, and has good stability.
Purpose: N(alpha)-fmoc-N(omega)-tosyl-L-arginine is a commonly used amino acid protecting group, which can be used in peptide synthesis and protein engineering. It can protect the amino group of arginine from reaction with other reactants, so as to realize selective synthesis and modification.
Preparation Method: In general, the synthesis of N(alpha)-fmoc-N(omega)-tosyl-L-arginine is carried out by first reacting with fluorenol to produce N(alpha)-fmoc-N(omega)-tosyl-L-arginine fluorenylmethyl ester, followed by acid hydrolysis to obtain the target product. This synthetic route requires certain operational skills and laboratory equipment.
Safety Information: For specific safety information about N(alpha)-fmoc-N(omega)-tosyl-L-arginine, please read the Safety Data Sheet (SDS) for the relevant chemical. When using and handling, please follow the laboratory's safe operating procedures, wear appropriate protective equipment, and ensure that the operation is carried out under well-ventilated conditions.
Last Update：2024-04-10 22:29:15
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