Nμ-Boc-N,N-phthaloylhydrazine, N-(tert-Butoxycarbonylamino)phthalimide - Names and Identifiers
Name | N-(Boc-amino)phthalimide
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Synonyms | 104188 N-(BOC-AMINO)PHTHALIMIDE N-(Boc-amino)phthalimide N-Boc-N-TCP N-(Boc-amino)phthalimide tert-butyl 1,3-dioxoisoindolin-2-ylcarbaMate tert-butyl N-(1,3-dioxoisoindol-2-yl)carbamate Carbamic acid,N-(1,3-dihydro-1,3-dioxo-2H-isoindol-2- tert-Butyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)carbamate Nμ-Boc-N,N-phthaloylhydrazine, N-(tert-Butoxycarbonylamino)phthalimide Carbamic acid,N-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 1,1-dimethylethyl ester
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CAS | 34387-89-8
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Nμ-Boc-N,N-phthaloylhydrazine, N-(tert-Butoxycarbonylamino)phthalimide - Physico-chemical Properties
Molecular Formula | C13H14N2O4
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Molar Mass | 262.26 |
Density | 1.32±0.1 g/cm3(Predicted) |
Melting Point | 140-145°C |
Solubility | tetrahydrofuran: 50mg/mL, clear, colorless |
pKa | 7.46±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Use | This product is for scientific research only and shall not be used for other purposes. |
Nμ-Boc-N,N-phthaloylhydrazine, N-(tert-Butoxycarbonylamino)phthalimide - Risk and Safety
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
Nμ-Boc-N,N-phthaloylhydrazine, N-(tert-Butoxycarbonylamino)phthalimide - Introduction
Tert-butyl 1,3-dioxoisoindoline-2-carbamate (N-Boc-N-TCP), also known as N-(Boc-amino)phthalimide, is an organic compound. It has a molecular formula of C16H19NO5 and a molecular weight of 309.33g/mol.
Nature:
N-Boc-N-TCP is a solid compound with a white or off-white crystalline form. It has low solubility and is relatively stable at room temperature. Its melting point is about 90-93°C.
Use:
N-Boc-N-TCP is an important intermediate in organic synthesis. It can be used as a protective group in the synthesis of drugs, which can protect the amino group from unnecessary reactions during the synthesis. The compound is widely used in the pharmaceutical industry.
Preparation Method:
A common method for preparing N-Boc-N-TCP is to react indole with methylene chloride anhydride to obtain indole carboxylic anhydride, and then react with a Boc-protected amine to generate the final product N-Boc-N-TCP.
Safety Information:
N-Boc-N-TCP are generally safe for proper use and storage. But as a chemical, it still needs to be treated properly. During operation, protective gloves, goggles and protective clothing should be worn to avoid direct contact. At the same time, it should be operated in a well-ventilated environment to avoid inhalation of dust or gas. If necessary, the relevant safety procedures and recommendations should be followed.
Last Update:2024-04-09 21:11:58