N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester
N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester
CAS: 115520-21-3
Molecular Formula: C43H30F5NO4S
N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester - Names and Identifiers
| Name | N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester |
| Synonyms | Fmoc-Cys(Trt)-OPfp FMOC-CYS(TRT)-OPFP FMOC-L-CYS(TRT)-OPFP FMOC-CYSTEINE(TRT)-OPFP FMOC-S-TRITYL-L-CYSTEINE PENTAFLUOROPHENYL ESTER Nα-Fmoc-S-trityl-L-cysteine pentafluorophenyl ester nα-fmoc-s-trityl-l-cysteine pentafluorophenyl ester N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE PENTAFLUOROPHENYL ESTER N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-cysteinate N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE PENTAFLUORPHENYL ESTER N-alpha-(9-fluorenylmethyloxycarbonyl)-S-trityl-L-cysteine pentafluorphenyl ester |
| CAS | 115520-21-3 |
| InChI | InChI=1/C43H30F5NO4S/c44-35-36(45)38(47)40(39(48)37(35)46)53-41(50)34(49-42(51)52-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-54-43(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,49,51)/t34-/m0/s1 |
N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester - Physico-chemical Properties
| Molecular Formula | C43H30F5NO4S |
| Molar Mass | 751.76 |
| Density | 1.359±0.06 g/cm3(Predicted) |
| Melting Point | 71-73 °C |
| Boling Point | 803.5±65.0 °C(Predicted) |
| Flash Point | 439.749°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Powder |
| BRN | 4225739 |
| pKa | 10.09±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.62 |
| MDL | MFCD00065639 |
| Use | An Fmoc protected cysteine derivative |
N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2930 90 16 |
N(alpha)-fmoc-S-trityl-L-cysteine penta-fluorophenyl ester - Introduction
N-fluorenylmethoxycarbonyl-S-trityl-L-cysteine pentafluorophenyl ester, also known as FMOC-cysteine pentafluorophenyl ester, is an organic synthesis reagent.
Properties: FMOC-cysteine pentafluorophenyl ester is a white solid with a higher melting point and lower volatility. It is stable at room temperature and is not easily decomposed under light and heat conditions.
Uses: FMOC-cysteine pentafluorophenyl ester is mainly used in the field of solid phase synthesis and peptide synthesis. It can be used as a protective group of amino acids for the synthesis of peptide chains, which can be linked to other amino acids after deprotection by acids or enzymes. It can also be used to synthesize proteins, study protein construction and function, etc.
Preparation Method: The preparation of FMOC-cysteine pentafluorophenyl ester is generally carried out by a chemical synthesis method. Specific methods generally involve reacting FMOC-cysteine with a pentafluorophenyl ester to form FMOC-cysteine pentafluorophenyl ester.
Safety Information: FMOC-Cysteine pentafluorophenyl ester generally has low toxicity, but due to its strong fragrance, it may be irritating to the skin and eyes. Wear gloves and goggles during use and ensure that the operation is carried out in a well-ventilated laboratory environment. If inhaled, touched or ingested, seek medical help immediately.
Properties: FMOC-cysteine pentafluorophenyl ester is a white solid with a higher melting point and lower volatility. It is stable at room temperature and is not easily decomposed under light and heat conditions.
Uses: FMOC-cysteine pentafluorophenyl ester is mainly used in the field of solid phase synthesis and peptide synthesis. It can be used as a protective group of amino acids for the synthesis of peptide chains, which can be linked to other amino acids after deprotection by acids or enzymes. It can also be used to synthesize proteins, study protein construction and function, etc.
Preparation Method: The preparation of FMOC-cysteine pentafluorophenyl ester is generally carried out by a chemical synthesis method. Specific methods generally involve reacting FMOC-cysteine with a pentafluorophenyl ester to form FMOC-cysteine pentafluorophenyl ester.
Safety Information: FMOC-Cysteine pentafluorophenyl ester generally has low toxicity, but due to its strong fragrance, it may be irritating to the skin and eyes. Wear gloves and goggles during use and ensure that the operation is carried out in a well-ventilated laboratory environment. If inhaled, touched or ingested, seek medical help immediately.
Last Update：2024-04-09 21:04:16
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