N-(4-acetyl-2-methylphenyl)acetamide
N-(4-acetyl-2-methylphenyl)acetamide
CAS: 40664-73-1
Molecular Formula: C11H13NO2
N-(4-acetyl-2-methylphenyl)acetamide - Names and Identifiers
| Name | N-(4-acetyl-2-methylphenyl)acetamide |
| Synonyms | N-(4-acetyl-2-methylphenyl)acetamide 4'-acetylamino-3'-methyl-acetophenone Acetamide, N-(4-acetyl-2-methylphenyl)- |
| CAS | 40664-73-1 |
N-(4-acetyl-2-methylphenyl)acetamide - Physico-chemical Properties
| Molecular Formula | C11H13NO2 |
| Molar Mass | 191.23 |
| Density | 1.122±0.06 g/cm3(Predicted) |
| Boling Point | 379.7±30.0 °C(Predicted) |
| pKa | 14.60±0.70(Predicted) |
N-(4-acetyl-2-methylphenyl)acetamide - Upstream Downstream Industry
| Downstream Products | 4'-Bromo-3'-methylacetophenone |
N-(4-acetyl-2-methylphenyl)acetamide - Introduction
N-(4-acetyl-2-methylphenyl)acetamide, also known as N-(4-acetyl-2-methylphenyl)acetamide.
Nature:
N-(4-acetyl-2-methylphenyl)acetamide is a colorless solid with a special chemical structure. Its molecular formula is C12H13NO2 and its molecular weight is 203.24g/mol. It is soluble in various organic solvents such as chloroform, dimethyl sulfoxide and ethanol at room temperature.
Use:
N-(4-acetyl-2-methylphenyl)acetamide can be used as a starting material for the synthesis of pharmaceutical intermediates and organic synthesis reactions. It has certain applications in the field of medicine, and can be used to synthesize compounds with biological activity.
Method:
The preparation method of N-(4-acetyl-2-methylphenyl)acetamide can be carried out by the following steps:
1. First, P-toluidine reacts with methylene ketone to generate N-(4-acetylphenyl)methanamine.
2. Then, under alkaline conditions, N-(4-acetylphenyl)methanamine is reacted with acetic anhydride to produce the final product N-(4-acetyl-2-methylphenyl)acetamide.
Safety Information:
N-(4-acetyl-2-methylphenyl)acetamide is a chemical that needs to be safe when used. It may be irritating to the eyes, skin and respiratory tract, so contact should be avoided during operation. Wear appropriate personal protective equipment, such as lab gloves, glasses and protective masks, and ensure that the operation is carried out in a well-ventilated place.
Nature:
N-(4-acetyl-2-methylphenyl)acetamide is a colorless solid with a special chemical structure. Its molecular formula is C12H13NO2 and its molecular weight is 203.24g/mol. It is soluble in various organic solvents such as chloroform, dimethyl sulfoxide and ethanol at room temperature.
Use:
N-(4-acetyl-2-methylphenyl)acetamide can be used as a starting material for the synthesis of pharmaceutical intermediates and organic synthesis reactions. It has certain applications in the field of medicine, and can be used to synthesize compounds with biological activity.
Method:
The preparation method of N-(4-acetyl-2-methylphenyl)acetamide can be carried out by the following steps:
1. First, P-toluidine reacts with methylene ketone to generate N-(4-acetylphenyl)methanamine.
2. Then, under alkaline conditions, N-(4-acetylphenyl)methanamine is reacted with acetic anhydride to produce the final product N-(4-acetyl-2-methylphenyl)acetamide.
Safety Information:
N-(4-acetyl-2-methylphenyl)acetamide is a chemical that needs to be safe when used. It may be irritating to the eyes, skin and respiratory tract, so contact should be avoided during operation. Wear appropriate personal protective equipment, such as lab gloves, glasses and protective masks, and ensure that the operation is carried out in a well-ventilated place.
Last Update：2024-04-09 21:01:54
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