N-α-Carbobenzoxy-4-chloro-L-phenylalanine - Names and Identifiers
N-α-Carbobenzoxy-4-chloro-L-phenylalanine - Physico-chemical Properties
Molecular Formula | C17H16ClNO4
|
Molar Mass | 333.77 |
Storage Condition | 2-8°C |
N-α-Carbobenzoxy-4-chloro-L-phenylalanine - Introduction
N-Benzyloxycarbonyl-3-(4-N-Benzyloxycarbonyl-3)-L-alanine (L-alanine) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid.
-Molecular formula: C16H14ClNO4.
-Molecular weight: 319.74g/mol.
-Melting point: 118-120 ℃.
-Soluble: Soluble in ethanol and dichloromethane.
Use:
- N-Benzyloxycarbonyl-3-(4-chlorophenyl)-L-alanine is an amino acid protecting group, which is often used to protect the amino group in amino acids or peptides in organic synthesis to prevent non-specific reactions.
-It can also be used as an intermediate in drug synthesis.
Method:
The preparation of N-Benzyloxycarbonyl-3-(4-chroophenyl)-L-alanine is usually carried out by the following steps:
1. First, L-4-chlorophenylalanine is acylated with acetone to generate an acylated product.
2. Then, the generated acylated product is condensed with benzyl alcohol to generate N-Benzyloxycarbonyl-3-(4-chlorohenyl)-L-alanine under alkali catalysis.
Safety Information:
- N-Benzyloxycarbonyl-3-(4-chorophenyl)-L-alanine safety data is limited, so appropriate safety protection measures should be taken when using it.
-During operation, avoid inhalation, contact with skin and ingestion.
-Personal protective equipment such as goggles, gloves and lab coats should be used when working with this compound.
-When storing and handling, it should be stored in a dry and ventilated place, and away from fire and oxidizing agents.
Please note that the information provided above is for reference only. The specific experimental operation and safety protection should follow the laboratory's safety operation specifications.
Last Update:2024-04-09 21:01:54