N-甲酰-L-亮氨酸
N-Formyl-L-leucine
CAS: 6113-61-7
Molecular Formula: C7H13NO3
N-甲酰-L-亮氨酸 - Names and Identifiers
| Name | N-Formyl-L-leucine |
| Synonyms | FOR-LEU-OH NSC 334321 N-Formylleucine N-formylleucine N-Formyl-Leu-OH FORMYL-L-ALANINE FORMYL-L-LEUCINE N-Formyl-L-leucine N-FORMYL-L-LEUCINE N-Formyl-S-leucine N-ALPHA-FORMYL-L-LEUCINE |
| CAS | 6113-61-7 |
| EINECS | 228-080-4 |
| InChI | InChI=1/C7H13NO3/c1-5(2)3-6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1 |
N-甲酰-L-亮氨酸 - Physico-chemical Properties
| Molecular Formula | C7H13NO3 |
| Molar Mass | 159.18 |
| Density | 1.2013 (rough estimate) |
| Melting Point | 142 °C |
| Boling Point | 284.67°C (rough estimate) |
| Flash Point | 171.915°C |
| Water Solubility | 29.45g/L(temperature not stated) |
| Solubility | Ethanol (Sparingly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder |
| Color | white |
| pKa | 3.51±0.21(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | -39.5 ° (C=1, H2O) |
| MDL | MFCD00055861 |
N-甲酰-L-亮氨酸 - Risk and Safety
| WGK Germany | 1 |
| Hazard Class | IRRITANT |
N-甲酰-L-亮氨酸 - Reference Information
| Application | N-formyl-L-leucine is an organic intermediate, it can be prepared from L-leucine as a starting material in one step. It has been reported in the literature that it can be used for the preparation of statins. |
| preparation | to L-leucine (1.31g,10mmol) in formic acid (50ml) at 0 °c acetic anhydride (28ml, 300mmol) was added dropwise to The stirred solution. After addition of acetic anhydride, the solution was stirred overnight at room temperature. The solution was treated with water (40ml). The solvent was removed under reduced pressure to give a white residue. The residue was recrystallized from water to give N-formyl-L-leucine. |
Last Update：2024-04-09 21:11:58
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