N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea - Names and Identifiers

Name	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
Synonyms	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea Urea, N-(2-chloro-6-methylphenyl)-N'-4-pyridinyl-
CAS	97627-24-2

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea - Physico-chemical Properties

Molecular Formula	C13H12ClN3O
Molar Mass	261.71
Storage Condition	-20℃
In vivo study	Compound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials.

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea - Preparation solution concentration reference

	1mg	5mg	10mg
1 mM	3.821 ml	19.105 ml	38.211 ml
5 mM	0.764 ml	3.821 ml	7.642 ml
10 mM	0.382 ml	1.911 ml	3.821 ml
5 mM	0.076 ml	0.382 ml	0.764 ml

Last Update：2024-01-02 23:10:35

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea - Reference Information

biological activity

N-[(1R)-4-[(aminominomethyl) amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-Alpha-phenylbenzenaceetamide is an anticonvulsant, there is potential to study extensive tonic and partial seizure clonic.

Last Update：2024-04-09 19:05:17