N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide - Names and Identifiers
N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide - Physico-chemical Properties
Molecular Formula | C18H19N5O5
|
Molar Mass | 385.37 |
Density | 1.59±0.1 g/cm3(Predicted) |
pKa | 7.87±0.43(Predicted) |
Storage Condition | Room Temprature |
N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide - Introduction
N6-Benzoyl-2 '-O-methyl-adenosine, abbreviated as 6BzAOMeA, is a chemical compound. Its structure contains the nucleotide group of adenosine and a benzoyl group, as well as a methoxy group attached at the 2 '-position of the ribose.
Its properties are as follows:
-Appearance: White or off-white solid
-Solubility: Soluble in water and organic solvents (such as methanol, dimethyl sulfoxide, etc.)
-Melting point: about 165-170°C
N6-Benzoyl-2 '-O-methyl-adenosine are mainly used in the field of chemical biology and medicinal chemistry research. As a modified group, it is often used to synthesize and study the structure and function of adenosine compounds. In addition, it can also be used for synthetic natural products and drug simulators.
preparation method can generally be carried out by chemical synthesis, the specific method is more complex, the need for multi-step reaction. One synthetic method is to react adenosine with p-toluoyl chloride (or p-toluic acid), react under basic conditions to produce N6-benzoyladenosine, and then react with methanol to give N6-Benzoyl-2 '-O-methyl-adenosine.
For safety information, N6-Benzoyl-2 '-O-methyl-adenosine are chemicals under normal laboratory conditions and should comply with the appropriate laboratory safety practices. It may cause irritation to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment during use, such as laboratory gloves, protective glasses and masks. Should be stored in a dry, cool place, and away from combustible and flammable materials. Specific safety information should be evaluated and followed based on the safety data sheets provided by the specific chemical supplier.
Last Update:2024-04-09 21:54:55