N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER
N-(tert-butoxycarbonyl)-D-serine methyl ester
CAS: 95715-85-8
Molecular Formula: C9H17NO5
N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER - Names and Identifiers
| Name | N-(tert-butoxycarbonyl)-D-serine methyl ester |
| Synonyms | BOC-D-SER-OME Boc-D-Ser-OMe N-BOC-D-ser-methylester BOC-D-SERINE METHYL ESTER boc-D-serine methyl ester N-BOC-D-serine methylester N-Boc-D-serine methyl ester BOC-D-SERINE METHYLESTER OIL N-(tert-butoxycarbonyl)-D-serine methyl ester N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER N-(TERT-BBUTOXYCARBONYL)-L-SERINE METHYL ESTER D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester (9CI) |
| CAS | 95715-85-8 |
| EINECS | 810-610-6 |
| InChI | InChI=1/C9H17NO5/c1-9(2,3)15-8(13)10-6(5-11)7(12)14-4/h6,11H,5H2,1-4H3,(H,10,13)/t6-/m1/s1 |
| InChIKey | SANNKFASHWONFD-ZCFIWIBFSA-N |
N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER - Physico-chemical Properties
| Molecular Formula | C9H17NO5 |
| Molar Mass | 219.24 |
| Density | 1.08g/mLat 25°C(lit.) |
| Boling Point | 215°C(lit.) |
| Flash Point | >230°F |
| Solubility | Chloroform, Methanol |
| Vapor Presure | 1.94E-06mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to yellow |
| pKa | 10.70±0.46(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.453(lit.) |
N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29241990 |
N-(TERT-BUTOXYCARBONYL)-D-SERINE METHYL ESTER - Introduction
N-(tert-butoxycarbonyl)-D-serine methyl ester is an organic compound with a chemical formula of C11H19NO6 and a molecular weight of 261.27. It is a colorless crystalline solid.
Nature:
N-(tert-butoxycarbonyl)-D-serine methyl ester is a stable compound, soluble in organic solvents such as chloroform and dimethylformamide, and insoluble in water. It is an odorless compound.
Use:
N-(tert-butoxycarbonyl)-D-serine methyl ester is widely used as a protecting group in chemical synthesis. It can protect the hydroxyl function of serine (Ser) in the synthesis of polypeptides and proteins. If desired, the protecting group can be removed with acid or enzyme to obtain the individual serine.
Preparation Method:
N-(tert-butoxycarbonyl)-D-serine methyl ester is usually prepared by adding tert-butoxycarbonyl chloroformic acid (tert-butoxycarbonyl chloride) to the reaction of D-serine methyl ester (D-serine methyl ester). After the reaction, the product is obtained and purified by crystallization.
Safety Information:
N-(tert-butoxycarbonyl)-D-serine methyl ester is generally a relatively safe compound under routine experimental operating conditions. However, it is still a chemical substance and should follow laboratory safety procedures. It is recommended to wear appropriate personal protective equipment, such as laboratory glasses, gloves and laboratory coats.
Nature:
N-(tert-butoxycarbonyl)-D-serine methyl ester is a stable compound, soluble in organic solvents such as chloroform and dimethylformamide, and insoluble in water. It is an odorless compound.
Use:
N-(tert-butoxycarbonyl)-D-serine methyl ester is widely used as a protecting group in chemical synthesis. It can protect the hydroxyl function of serine (Ser) in the synthesis of polypeptides and proteins. If desired, the protecting group can be removed with acid or enzyme to obtain the individual serine.
Preparation Method:
N-(tert-butoxycarbonyl)-D-serine methyl ester is usually prepared by adding tert-butoxycarbonyl chloroformic acid (tert-butoxycarbonyl chloride) to the reaction of D-serine methyl ester (D-serine methyl ester). After the reaction, the product is obtained and purified by crystallization.
Safety Information:
N-(tert-butoxycarbonyl)-D-serine methyl ester is generally a relatively safe compound under routine experimental operating conditions. However, it is still a chemical substance and should follow laboratory safety procedures. It is recommended to wear appropriate personal protective equipment, such as laboratory glasses, gloves and laboratory coats.
Last Update：2024-04-10 22:29:15
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