N-Boc-Piperidine-2-carboxylate or ethyl 1-Boc-piperidine-2-carboxylate
Ethyl 1-Boc-piperidine-2-carboxylate
CAS: 362703-48-8
Molecular Formula: C13H23NO4
N-Boc-Piperidine-2-carboxylate or ethyl 1-Boc-piperidine-2-carboxylate - Names and Identifiers
N-Boc-Piperidine-2-carboxylate or ethyl 1-Boc-piperidine-2-carboxylate - Physico-chemical Properties
| Molecular Formula | C13H23NO4 |
| Molar Mass | 257.33 |
| Density | 1.077±0.06 g/cm3(Predicted) |
| Boling Point | 323.9±35.0 °C(Predicted) |
| Flash Point | 149.7°C |
| Vapor Presure | 0.000254mmHg at 25°C |
| pKa | -3.16±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.473 |
N-Boc-Piperidine-2-carboxylate or ethyl 1-Boc-piperidine-2-carboxylate - Introduction
Ethyl is an organic compound, commonly abbreviated as Boc-2-Pip-OEt. Its chemical formula is C12H21NO3 and its molecular weight is 227.3g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: a colorless to light yellow liquid
-Melting Point: Not Applicable
-Boiling point: approximately 106-108°C
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide
Use:
- Ethyl is often used as an intermediate in organic synthesis.
-Because of the Boc protecting group, it can protect the amino group on the piperidine during the synthesis of the compound.
-It is commonly used in the preparation of active raw materials, drugs and pesticides in the pharmaceutical field.
Preparation Method:
Ethyl's preparation method can be carried out by the following steps:
1. Add acetyl chloride, sulfonyl chloride and tetrahydrofuran (THF) to dimethylformamide (DMF).
2. At low temperature, piperidine is added to the reaction system to react with the ions in DMF to generate piperidine formyl ethyl chloride.
3. Add piperidinecarboxylethyl chloride to ethylide benzoate (Boc2O) and alkali solution to generate Ethyl.
Safety Information:
- Ethyl is a chemical that requires appropriate laboratory safety and personal protective measures.
-Contact with skin may cause irritation. Wear goggles, lab coat, protective gloves, etc.
-Avoid inhaling the vapors or dust of the compound, and avoid ingestion or getting into the eyes.
-Store away from fire, high temperature and oxidizing agents.
-Regarding the specific use and treatment methods, the operation should be carried out in accordance with the safety data sheet of the chemical, and in accordance with relevant regulations and regulations.
Nature:
-Appearance: a colorless to light yellow liquid
-Melting Point: Not Applicable
-Boiling point: approximately 106-108°C
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide
Use:
- Ethyl is often used as an intermediate in organic synthesis.
-Because of the Boc protecting group, it can protect the amino group on the piperidine during the synthesis of the compound.
-It is commonly used in the preparation of active raw materials, drugs and pesticides in the pharmaceutical field.
Preparation Method:
Ethyl's preparation method can be carried out by the following steps:
1. Add acetyl chloride, sulfonyl chloride and tetrahydrofuran (THF) to dimethylformamide (DMF).
2. At low temperature, piperidine is added to the reaction system to react with the ions in DMF to generate piperidine formyl ethyl chloride.
3. Add piperidinecarboxylethyl chloride to ethylide benzoate (Boc2O) and alkali solution to generate Ethyl.
Safety Information:
- Ethyl is a chemical that requires appropriate laboratory safety and personal protective measures.
-Contact with skin may cause irritation. Wear goggles, lab coat, protective gloves, etc.
-Avoid inhaling the vapors or dust of the compound, and avoid ingestion or getting into the eyes.
-Store away from fire, high temperature and oxidizing agents.
-Regarding the specific use and treatment methods, the operation should be carried out in accordance with the safety data sheet of the chemical, and in accordance with relevant regulations and regulations.
Last Update：2024-04-09 21:04:16
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Product Name: Ethyl 1-Boc-piperidine-2-carboxylate Visit Supplier Webpage Request for quotationCAS: 362703-48-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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