N-Boc-trans-1,2-cyclohexanediamine

N-Boc-trans-1,2-cyclohexanediamine - Names and Identifiers

Name	1-N-BOC-1,2-TRANS-CYCLOHEXYLDIAMINE
Synonyms	N-Boc-trans-1,2-cyclohexanediamine N-BOC-TRANS-1,2-DIAMINOCYCLOHEXANE Trans-N-Boc-1,2-Cyclohexanediamine TRANS-N-BOC-1,2-DIAMINOCYCLOHEXANE N-Boc-trans-1,2-diamino-cyclohexane 1-N-BOC-1,2-TRANS-CYCLOHEXYLDIAMINE 1-N-BOC-1(R), 2(R)-CYCLOHEXYLDIAMINE tert-butyl [(1R,2R)-2-aminocyclohexyl]carbamate trans-(2-Amino-cyclohexyl)-carbamic acid tert-butyl ester Carbamic acid, N-[(1R,2R)-2-aminocyclohexyl]-, 1,1-dimethylethyl ester, rel-
CAS	137731-41-0
InChI	InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8(9)12/h8-9H,4-7,12H2,1-3H3,(H,13,14)/t8-,9-/m1/s1

N-Boc-trans-1,2-cyclohexanediamine - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	1.02±0.1 g/cm3(Predicted)
Boling Point	322.1±31.0 °C(Predicted)
Flash Point	148.6°C
Vapor Presure	0.000286mmHg at 25°C
pKa	12.26±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.488

N-Boc-trans-1,2-cyclohexanediamine - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3259
Hazard Class	IRRITANT

N-Boc-trans-1,2-cyclohexanediamine - Introduction

N-tert-butoxycarbonyl-trans-1, 2-cyclohexanediamine (abbreviated tBOC-1,2-cyclohexanediamine) is an organic compound. Its chemical formula is C11H21NO2 and its molecular weight is 199.29g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
- tBOC-1, 2-cyclohexanediamine is a solid crystal with a white or off-white appearance.
-It is stable at room temperature, but may decompose at high temperatures. The
- tBOC group can be easily deprotected under basic conditions, thereby reducing to 1,2-cyclohexanediamine.

Use:
- tBOC-1, 2-cyclohexanediamine is an important organic synthesis intermediate, which is widely used in the fields of medicine and chemical industry.
-It can be used for the synthesis of peptides, drug molecules and other organic compounds.
-It can also be used as a skeleton molecule to build complex organic molecules.

Preparation Method:
- tBOC-1, the preparation of 2-cyclohexanediamine can be achieved by a variety of methods. The more commonly used method is to react 1,2-cyclohexanediamine with t-tert-butoxycarbonyl chloride (BOC-Cl) under alkaline conditions.
-The reaction is generally carried out at room temperature, and after the completion of the reaction, it is treated with acid to remove the remaining protecting group.

Safety Information:
- tBOC-1, 2-cyclohexanediamine is less toxic, but general laboratory safety procedures should still be followed.
-Avoid inhalation, ingestion or contact with skin and eyes during operation.
-Waste disposal shall comply with local regulatory standards.

Please note that any operations in chemical experiments should be carried out under suitable laboratory conditions and follow relevant safety operating guidelines and regulations.

Last Update：2024-04-09 15:17:52