N-Cbz-N'-Boc-ethylenediamine
N-Cbz-N'-Boc-ethylenediamine
CAS: 77153-05-0
Molecular Formula: C15H22N2O4
N-Cbz-N'-Boc-ethylenediamine - Names and Identifiers
| Name | N-Cbz-N'-Boc-ethylenediamine |
| Synonyms | N-Cbz-N'-Boc-ethylenediamine 1-CBZ-AMINO-2-BOC-AMINO-ETHANE Benzyl tert-butyl ethane-1,2-diyldicarbamate N1-benzyloxycarbonyl-N2-t-butoxycarbonyl-1,2-ethanediamine N-(Benzyloxycarbonyl)-N'-(tert-butoxycarbonyl)ethylenediamine [[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-ETHYL]-CARBAMIC ACID PHENYLMETHYL ESTER Carbamic acid, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, phenylmethyl ester |
| CAS | 77153-05-0 |
N-Cbz-N'-Boc-ethylenediamine - Physico-chemical Properties
| Molecular Formula | C15H22N2O4 |
| Molar Mass | 294.35 |
| Density | 1.121 |
| Melting Point | 123-124 ºC |
N-Cbz-N'-Boc-ethylenediamine - Introduction
N-Cbz-N '-Boc-ethylenediamine (N-Cbz-N'-Boc-ethylenediamine) is an organic compound containing an ethylenediamine molecule and the substituents benzyl (Cbz) and tert-butoxycarbonyl (Boc) in its chemical structure.
Nature:
N-Cbz-N '-Boc-ethylenediamine is a colorless to slightly yellow solid, soluble in some common organic solvents, such as dimethyl sulfoxide and ethanol. It is relatively stable at room temperature, but may decompose under high temperature conditions or in the presence of organic bases.
Use:
N-Cbz-N '-Boc-ethylenediamine is often used in organic synthesis as a medium that can provide ethylenediamine groups. It can be used as an amino protecting group to protect the reactivity of the amino group, and the protecting group can be removed by appropriate conditions when necessary. In addition, N-Cbz-N '-Boc-ethylenediamine can also be used in the synthesis of intermediates used in pharmaceutical research or in the preparation of other organic compounds.
Preparation Method:
N-Cbz-N '-Boc-ethylenediamine usually reacts with N-phenyldioxymethylamine (Cbz-CH-NH₂) under appropriate conditions to introduce benzyl and tert-butoxycarbonyl groups into the ethylenediamine molecule.
Safety Information:
N-Cbz-N '-The safety of the Boc-ethylenediamine is high, but it is still necessary to pay attention to proper operation and storage methods to avoid contact and inhalation of substances. Wear appropriate protective equipment such as lab gloves, goggles, and lab hood during use. In addition, contact with oxidants and strong acids should be avoided to avoid dangerous reactions.
Nature:
N-Cbz-N '-Boc-ethylenediamine is a colorless to slightly yellow solid, soluble in some common organic solvents, such as dimethyl sulfoxide and ethanol. It is relatively stable at room temperature, but may decompose under high temperature conditions or in the presence of organic bases.
Use:
N-Cbz-N '-Boc-ethylenediamine is often used in organic synthesis as a medium that can provide ethylenediamine groups. It can be used as an amino protecting group to protect the reactivity of the amino group, and the protecting group can be removed by appropriate conditions when necessary. In addition, N-Cbz-N '-Boc-ethylenediamine can also be used in the synthesis of intermediates used in pharmaceutical research or in the preparation of other organic compounds.
Preparation Method:
N-Cbz-N '-Boc-ethylenediamine usually reacts with N-phenyldioxymethylamine (Cbz-CH-NH₂) under appropriate conditions to introduce benzyl and tert-butoxycarbonyl groups into the ethylenediamine molecule.
Safety Information:
N-Cbz-N '-The safety of the Boc-ethylenediamine is high, but it is still necessary to pay attention to proper operation and storage methods to avoid contact and inhalation of substances. Wear appropriate protective equipment such as lab gloves, goggles, and lab hood during use. In addition, contact with oxidants and strong acids should be avoided to avoid dangerous reactions.
Last Update：2024-04-09 20:52:54
