N-Fmoc-D-aspartic acid 4-benzyl ester - Names and Identifiers
N-Fmoc-D-aspartic acid 4-benzyl ester - Physico-chemical Properties
Molecular Formula | C26H23NO6
|
Molar Mass | 445.46 |
Density | 1.310±0.06 g/cm3(Predicted) |
Boling Point | 687.2±55.0 °C(Predicted) |
Appearance | Solid |
pKa | 3.54±0.23(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
N-Fmoc-D-aspartic acid 4-benzyl ester - Introduction
Fmoc-D-Asp (OBzl)-OH(Fmoc-D-Asp (OBzl)-OH) is an organic compound whose Properties, Uses, preparation and safety information are as follows:
Nature:
-chemical formula: C37H29NO7
-Molecular weight: 587.63g/mol
-Appearance: White or yellowish solid
-Melting Point: 185-190 ° C
-Solubility: insoluble in water, soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane, etc.
Use:
- Fmoc-D-Asp(OBzl)-OH is an amino acid protecting group, mainly used in Solid Phase Peptide Synthesis (SPPS). It can protect the side chain carboxyl of D-Asp amino acids to prevent unnecessary reactions and side reactions. In the synthesis of polypeptides or proteins, Fmoc-D-Asp(OBzl)-OH can be used to introduce corresponding D-Asp residues.
Method:
- Fmoc-D-Asp(OBzl)-OH can be prepared by chemical synthesis. The target product is usually obtained by a series of reaction steps (esterification, introduction of protecting groups, deprotection, etc.) using the corresponding L-Asp as starting material.
Safety Information:
-The safety of Fmoc-D-Asp(OBzl)-OH has not been fully determined, so it is necessary to follow laboratory safety procedures when using it.
-Avoid contact with skin and eyes, and wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-Use should be carried out in a well-ventilated environment, avoid inhalation or intake.
-Do not mix with strong oxidants and strong acids to avoid possible dangerous reactions.
-Keep dry and sealed during storage and handling to avoid contact with other chemicals.
Last Update:2024-04-10 22:29:15