Name | N-methyl-N-(trimethylsilyl)trifluoroacetamide |
Synonyms | MSTFA N-methyl-n-trimethylsilyltrifluoroacetamide N-Methyl-N-(Trimethylsily)Trifluoroacetamide N-methyl-N-(trimethylsilyl)trifluoroacetamide MSTFA~N-Trimethylsilyl-N-methyltrifluoroacetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 98 N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACET-A MIDE, FOR GC N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO-ACE TAMIDE, DERIVATIZATION GRADE |
CAS | 24589-78-4 |
EINECS | 246-331-6 |
InChI | InChI=1/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3 |
InChIKey | MSPCIZMDDUQPGJ-UHFFFAOYSA-N |
Molecular Formula | C6H12F3NOSi |
Molar Mass | 199.25 |
Density | 1.075g/mLat 25°C(lit.) |
Melting Point | 98-100°C |
Boling Point | 130132°C |
Flash Point | 77°F |
Water Solubility | reacts |
Vapor Presure | 8.8 mm Hg ( 27 °C) |
Vapor Density | >1 (vs air) |
Appearance | Liquid |
Specific Gravity | 1.076 |
Color | Clear colorless to light yellow |
BRN | 1941550 |
pKa | -1.34±0.70(Predicted) |
Storage Condition | 2-8°C |
Sensitive | 7: reacts slowly with moisture/water |
Refractive Index | n20/D 1.383 |
MDL | MFCD00000411 |
Use | High-efficiency silanizing reagent for non-steroidal anti-inflammatory analgesics derived from active silanizing reagent. Suitable for amino, carboxyl, indolalkylamine, serotonin and tryptamine derivatization. |
Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R61 - May cause harm to the unborn child R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S16 - Keep away from sources of ignition. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S53 - Avoid exposure - obtain special instructions before use. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
RTECS | AC9800000 |
FLUKA BRAND F CODES | 10-21 |
TSCA | T |
HS Code | 29319090 |
Hazard Note | Flammable |
Hazard Class | 3 |
Packing Group | III |
Reference Show more | 1. Wang Xiaoyan, Shen Weijian, Wang Hong, et al. Determination of 10 Perfluorocarboxylic Acid Compounds in Water by Gas Chromatography-Negative Chemical Source-Mass Spectrometry [J]. Chromatography, 2019, 37(01):44-51. |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Use | Silane derivatization reagent in derivatization reagent for gas chromatography. The derivatization reaction between silylation reagent and sample compound is carried out by replacing the active hydrogen of hydroxyl, carboxyl, mercapto, amino and imino with silane group. The product of the derivatization reaction is a silyl ether or a silyl ester. Almost all compounds containing these active hydrogen can undergo derivative reactions with silanizing reagents, and the order of reaction activity: alcohol> phenol> carboxylic acid> amine> amide. High-efficiency silanization reagent, used for non-steroidal anti-inflammatory analgesics derived from active silanization reagent. Suitable for amino, carboxyl, indolalkylamine, serotonin and tryptamine derivatization. |