N-Methyl-2-piperidin-4-ylacetamide hydrochloride
N-Methyl-2-piperidin-4-ylacetamide hydrochloride
CAS: 70724-80-0
Molecular Formula: C8H16N2O
N-Methyl-2-piperidin-4-ylacetamide hydrochloride - Names and Identifiers
N-Methyl-2-piperidin-4-ylacetamide hydrochloride - Physico-chemical Properties
| Molecular Formula | C8H16N2O |
| Molar Mass | 156.23 |
| Density | 0.961±0.06 g/cm3(Predicted) |
| Boling Point | 327.7±15.0 °C(Predicted) |
| pKa | 16.35±0.46(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12028098 |
N-Methyl-2-piperidin-4-ylacetamide hydrochloride - Risk and Safety
| Hazard Class | IRRITANT |
N-Methyl-2-piperidin-4-ylacetamide hydrochloride - Introduction
N-Methyl-2-piperidin-4-ylacetamide hydrochloride (N-methyl-2-piperidin-4-ylacetamide hydrochloride) is an organic compound with a chemical formula of C8H16ClN2O and a relative molecular mass of 184.68.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride is a white solid, soluble in water and methanol. It is a quaternary ammonium salt whose cation is a positively charged quaternary nitrogen ion and the anion is a hydrochloride ion. It has polar and ionic properties, so it is widely used in organic synthesis.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride has important applications in the field of pharmacy. It is the precursor of lidocaine, a local anesthetic, and can be synthesized as an intermediate of lidocaine. Lidocaine is a drug used for local anesthesia and is often used in medical procedures such as surgery.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride are generally prepared by reacting 2-piperidinylacetamide with hydrochloric acid in methanol. The specific reaction steps are as follows:
1. Dissolve 2-piperidinylacetamide in methanol.
2. Add the hydrochloric acid solution slowly while stirring the reaction mixture.
3. After completion of the reaction, a N-Methyl-2-piperidin-4-ylacetamide hydrochloride was obtained by filtration, washing and drying.
It should be noted that the preparation process should be strictly operated, pay attention to the use of safety measures, to avoid the production of toxic gases and contact with the skin or inhalation caused by discomfort.
For safety information, N-Methyl-2-piperidin-4-ylacetamide the specific toxicity of the hydrochloride, potential hazards to humans and the environment may need to be understood in the safety data sheet. Therefore, it is recommended to consult the relevant safety information before use, and to ensure the environmental safety of the operation and the correct handling of the substance. Follow proper operating procedures and personal protective measures when handling and storing.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride is a white solid, soluble in water and methanol. It is a quaternary ammonium salt whose cation is a positively charged quaternary nitrogen ion and the anion is a hydrochloride ion. It has polar and ionic properties, so it is widely used in organic synthesis.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride has important applications in the field of pharmacy. It is the precursor of lidocaine, a local anesthetic, and can be synthesized as an intermediate of lidocaine. Lidocaine is a drug used for local anesthesia and is often used in medical procedures such as surgery.
N-Methyl-2-piperidin-4-ylacetamide hydrochloride are generally prepared by reacting 2-piperidinylacetamide with hydrochloric acid in methanol. The specific reaction steps are as follows:
1. Dissolve 2-piperidinylacetamide in methanol.
2. Add the hydrochloric acid solution slowly while stirring the reaction mixture.
3. After completion of the reaction, a N-Methyl-2-piperidin-4-ylacetamide hydrochloride was obtained by filtration, washing and drying.
It should be noted that the preparation process should be strictly operated, pay attention to the use of safety measures, to avoid the production of toxic gases and contact with the skin or inhalation caused by discomfort.
For safety information, N-Methyl-2-piperidin-4-ylacetamide the specific toxicity of the hydrochloride, potential hazards to humans and the environment may need to be understood in the safety data sheet. Therefore, it is recommended to consult the relevant safety information before use, and to ensure the environmental safety of the operation and the correct handling of the substance. Follow proper operating procedures and personal protective measures when handling and storing.
Last Update：2024-04-09 21:21:28
