N-cyclopropyl-4-(piperidin-3-ylMethyl)pyriMidin-2-aMine - Names and Identifiers
N-cyclopropyl-4-(piperidin-3-ylMethyl)pyriMidin-2-aMine - Physico-chemical Properties
Molecular Formula | C13H20N4
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Molar Mass | 232.32 |
N-cyclopropyl-4-(piperidin-3-ylMethyl)pyriMidin-2-aMine - Introduction
N-cyclopropyl-4-(3-piperidinomethyl)-2-pyrimidinamine is an organic compound with the formula C12H18N4 and a molecular weight of 226.30.
Nature:
N-cyclopropyl-4-(3-piperidinomethyl)-2-pyrimidinamine is a white or off-white crystalline powdery solid. It is difficult to dissolve in water, but it is soluble in organic solvents such as ethanol and chloroform. It has a certain alkalinity.
Use:
N-cyclopropyl-4-(3-piperidinomethyl)-2-pyrimidinamine is mainly used as a pharmaceutical intermediate. It is a synthetic raw material for anti-infective drugs, commonly used in the synthesis of pyrimidine antibiotics, antibacterial drugs and antiviral drugs.
Method:
The preparation of N-cyclopropyl-4-(3-piperidinomethyl)-2-pyrimidinamine can generally be accomplished by a multi-step reaction. A common synthetic method is to condense 3-piperidinomethylamine with cyclopentadienone to produce N-cyclopropyl-3-piperidinecarboxaldehyde, which is then reacted with 2-cyano-4-methylpyrimidine to give the final product.
Safety Information:
N-cyclopropyl-4-(3-piperidinomethyl)-2-pyrimidinamine is generally safe under normal conditions of use, but it still needs to be used and stored correctly. Avoid inhalation, swallowing, or contact with skin and eyes. Appropriate protective equipment, such as lab gloves and goggles, should be worn during operation. If you are exposed or unwell, you should seek medical attention immediately.
It should be noted that the above information is only a general introduction, specific use and handling should refer to the relevant chemical literature and safety data sheets. When conducting experiments or applications, it is recommended to conduct them under suitable facilities and conditions, and strictly abide by relevant regulations and safe operating procedures.
Last Update:2024-04-09 19:05:46