N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine - Names and Identifiers
Name | 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine
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Synonyms | Dmt-Ac-dC DMT-Ac-dC DMT-NAC-DC 5'-DMT-Ac-dC 5'-O-DMT-N4-Ac cytidine N-ACETYL-5'-DMT DEOXYCYTIDINE 5'-DMTr-N4-acetyl-2'-deoxycytidine N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine N4-Acetyl-2'-deoxy-5'-O-DMT-D-cytidine 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl cytidine N4-ACETYL-5'-(DIMETHOXYTRITYL)-2'-DEOXYCYTIDINE N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-ACETYL-2'-DEOXYCYTIDINE N4-Acetyl-5''-O-(4,4''-dimethoxytrityl)-2''-deoxycytidine Cytidine, N-acetyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]- DTN-003 5'-O-(4,4'-DiMethoxytrityl)-N4-Acetyl-2'-Deoxycytidine 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine (synthetic) 5''-O-(4,4''-Dimethoxytrityl)-N4-acetyl-2''-deoxycytidine (synthetic)
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CAS | 121058-82-0 100898-63-3
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EINECS | 2017-001-1 |
N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine - Physico-chemical Properties
Molecular Formula | C32H33N3O8
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Molar Mass | 587.62 |
Density | 1.32±0.1 g/cm3(Predicted) |
Appearance | White powder |
pKa | 10.21±0.20(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
MDL | MFCD05663669 |
Physical and Chemical Properties | Storage Conditions: Store dry at 2-8 ℃ |
N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine - Introduction
5 '-O-(4,4'-dimethoxytrityl)-N4-acetyl -2 '-deoxycytidine is an organic compound commonly abbreviated as DMTr-EdC.
Nature:
The compound is a white crystalline powder with high solubility. It is a nucleotide derivative that has the backbone structure of a nucleotide with functional groups such as acetyl and trityl.
Use:
DMTr-EdC are commonly used as protecting groups in the process of nucleic acid fluorescent labeling, DNA and RNA synthesis. It can improve the efficiency and purity of nucleic acid synthesis and help with experiments such as nucleic acid sequencing and gene analysis.
Preparation Method:
The method of synthesizing DMTr-EdC usually involves several reactions. First, DMTr-EdU(5 '-O-(4,4'-dimethoxytrityl)-N4-acetyl -2 '-deoxyuridine) is synthesized by a chemical reaction, and then hydrogen iodide is added under alkaline conditions to process the DMTr-EdU into DMTr-EdC.
Safety Information:
When using the DMTr-EdC, you need to follow basic laboratory safety procedures. This compound is generally considered to be relatively safe in analytical laboratories, but it is still necessary to avoid inhalation, contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during handling.
It should be emphasized that although DMTr-EdC are relatively safe in the laboratory, there may be specific risks and precautions when used in biological laboratories because of possible interactions with cells. According to the actual application, please refer to the chemical safety data sheet and laboratory safety guide during specific operation to ensure the safety of operation.
Last Update:2024-04-09 22:01:47