N6-Boc-D-lysine
H-D-Lys(Boc)-OH
CAS: 31202-69-4
Molecular Formula: C11H22N2O4
N6-Boc-D-lysine - Names and Identifiers
| Name | H-D-Lys(Boc)-OH |
| Synonyms | D-LYSINE(BOC) N-e-BOC-D-Lys H-D-Lys(Boc)-OH H-D-LYS(BOC)-OH N6-Boc-D-lysine D-LYSINE(BOC)-OH N-epsilon-Boc-D-lysine N-EPSILON-BOC-D-LYSINE N-Epsilon-Boc-D-Lysine N-EPSILON-T-BOC-D-LYSINE N-EPSILON-T-BUTOXYCARBONYL-D-LYSINE N-epsilon-t-Butyloxycarbonyl-D-lysine (2R)-2-ammonio-6-[(tert-butoxycarbonyl)amino]hexanoate |
| CAS | 31202-69-4 |
| InChI | InChI=1/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m1/s1 |
N6-Boc-D-lysine - Physico-chemical Properties
| Molecular Formula | C11H22N2O4 |
| Molar Mass | 246.3 |
| Density | 1.113±0.06 g/cm3(Predicted) |
| Boling Point | 412.9±40.0 °C(Predicted) |
| Flash Point | 203.5°C |
| Vapor Presure | 5.65E-08mmHg at 25°C |
| Appearance | Powder |
| Color | White |
| pKa | 2.53±0.24(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.485 |
N6-Boc-D-lysine - Risk and Safety
| HS Code | 29224999 |
N6-Boc-D-lysine - Introduction
H-D-Lys(Boc)-OH(H-D-Lys(Boc)-OH) is an organic compound that has the following properties and uses:
Nature:
-Appearance: Colorless or white crystalline powder
-Molecular formula: C17H31N3O5
-Molecular weight: 369.44g/mol
-Melting point: About 150-155 ° C
-Solubility: Soluble in acetic acid, dimethylformamide and formamide, slightly soluble in chloroform, almost insoluble in water
Use:
-Chemical synthesis: H-D-Lys(Boc)-OH is one of the commonly used protective amino acids in peptide chemical synthesis. It can protect the amino group on the amino acid side chain by replacing the hydroxyl group on D-lysine, thus preventing it from non-specific reaction with other reagents to ensure the selectivity of the target peptide in the synthesis process.
-Drug research and development: H-D-Lys(Boc)-OH is also widely used in drug research and development, such as as a protective agent in the synthesis of peptide drugs, the stability and biological activity of the drug can be increased.
Method:
The preparation of H-D-Lys(Boc)-OH is usually carried out by the following steps:
1. D-Lysine is dissolved in alcohol or other suitable solvent.
2. Add t-butyl carbamate (Boc2O) or other suitable acylating reagent to react with D-lysine.
3. After the reaction, the reaction mixture is acidified to remove unreacted reagents and intermediate products.
4. Purify the target product by crystallization or other methods.
Safety Information:
H-D-Lys(Boc)-OH is an organic compound, you need to pay attention to the following safety matters:
-avoid direct contact with skin and eyes, if accidentally contact, should immediately rinse with plenty of water.
-Wear appropriate personal protective equipment such as protective gloves, safety glasses and lab coat during operation.
-Operate in a well-ventilated laboratory to avoid inhaling its volatile products.
-Store away from fire sources and avoid contact with oxidants.
-Please read and follow the relevant safety instructions and operating procedures before use.
Nature:
-Appearance: Colorless or white crystalline powder
-Molecular formula: C17H31N3O5
-Molecular weight: 369.44g/mol
-Melting point: About 150-155 ° C
-Solubility: Soluble in acetic acid, dimethylformamide and formamide, slightly soluble in chloroform, almost insoluble in water
Use:
-Chemical synthesis: H-D-Lys(Boc)-OH is one of the commonly used protective amino acids in peptide chemical synthesis. It can protect the amino group on the amino acid side chain by replacing the hydroxyl group on D-lysine, thus preventing it from non-specific reaction with other reagents to ensure the selectivity of the target peptide in the synthesis process.
-Drug research and development: H-D-Lys(Boc)-OH is also widely used in drug research and development, such as as a protective agent in the synthesis of peptide drugs, the stability and biological activity of the drug can be increased.
Method:
The preparation of H-D-Lys(Boc)-OH is usually carried out by the following steps:
1. D-Lysine is dissolved in alcohol or other suitable solvent.
2. Add t-butyl carbamate (Boc2O) or other suitable acylating reagent to react with D-lysine.
3. After the reaction, the reaction mixture is acidified to remove unreacted reagents and intermediate products.
4. Purify the target product by crystallization or other methods.
Safety Information:
H-D-Lys(Boc)-OH is an organic compound, you need to pay attention to the following safety matters:
-avoid direct contact with skin and eyes, if accidentally contact, should immediately rinse with plenty of water.
-Wear appropriate personal protective equipment such as protective gloves, safety glasses and lab coat during operation.
-Operate in a well-ventilated laboratory to avoid inhaling its volatile products.
-Store away from fire sources and avoid contact with oxidants.
-Please read and follow the relevant safety instructions and operating procedures before use.
Last Update：2024-04-09 19:05:49
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