NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone - Names and Identifiers
NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone - Physico-chemical Properties
Molecular Formula | C10H10D3N3O2
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Molar Mass | 210.25 |
Appearance | neat |
Storage Condition | -20°C |
NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R22 - Harmful if swallowed
R43 - May cause sensitization by skin contact
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Safety Description | 36/37 - Wear suitable protective clothing and gloves.
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UN IDs | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone - Introduction
4-(Methyl-d3-nitrosalminol)-1-(3-pyridyl)-1-butanone, also known as n-nitroso nornicotinone-d3 (4-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanone), is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C11H11D3N2O2
-Molecular weight: 213.30g/mol
-Melting Point: 75-78 ℃
-Boiling point: 262.0±23.0 ℃ (predicted value)
-Solubility: Soluble in polar organic solvents such as ethanol, dimethyl sulfoxide
Use:
4-(Methyl-d3-nitro Saminol)-1-(3-pyridyl)-1-butanone is a compound containing the nitrogen -15 isotope, it is widely used as a marker compound in drug metabolism studies, pharmacokinetics and drug tolerance studies. It can be used to detect and quantify the metabolic pathways of compounds, metabolites and drug interactions with biological systems.
Method:
The preparation of 4-(methyl-d3-nitrosalminol)-1-(3-pyridyl)-1-butanone is usually carried out by organic synthetic chemistry methods. Specific synthetic routes and procedures may vary depending on the purpose and requirements of the study.
Safety Information:
Information regarding the safety and toxicity of 4-(methyl-d3-nitrosalminol)-1-(3-pyridyl)-1-butanone is insufficient. Since it is an isotopically containing compound, special attention should be paid to the safe handling and use of radioactive materials. During use and handling, laboratory safety procedures should be followed, and appropriate protective measures should be taken, including wearing gloves, laboratory glasses and protective clothing. If necessary, the operation should be carried out under professional guidance.
Last Update:2024-04-09 21:54:55