Name | DL-Norvaline |
Synonyms | DL-Norvaline NORVALINE, DL- DL-2-Aminovaleric acid α-DL-aminopentanoicacid DL-alpha-Aminovaleric acid Valeric acid, 2-amino-, DL- (R,S)-2-aminopentanoic acid alpha-DL-Aminopentanoic acid dl-alpha-Amino-N-valenic acid |
CAS | 760-78-1 |
EINECS | 212-082-7 |
InChI | InChI=1/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8) |
InChIKey | SNDPXSYFESPGGJ-UHFFFAOYSA-N |
Molecular Formula | C5H11NO2 |
Molar Mass | 117.15 |
Density | 1.2000 (estimate) |
Melting Point | 300℃ |
Boling Point | 222.9±23.0 °C(Predicted) |
Water Solubility | 1 g/10 mL (18℃) |
Appearance | Form Solid, color White to Off-White |
pKa | 2.36, 9.72(at 25℃) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.4650 (estimate) |
MDL | MFCD00064420 |
Physical and Chemical Properties | Bioactive DL-Norvaline (2-Aminopentanoic acid, H-DL-Nva-OH, 2-Aminovalic acid, α-Aminopentanoic acid) is an important drug intermediate. |
Use | Used as a drug Intermediate |
Hazard Symbols | Xn - Harmful |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R20/22 - Harmful by inhalation and if swallowed. |
Safety Description | S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29224995 |
Downstream Products | 2-Oxopentanoic acid 2-Bromovaleric acid |
Solubility | 83.9g/l |
optical rotation (optical activity) | [α]25/D 0.00±0.10°, c = 2 in 5 M HCl |
Merck | 14,6716 |
BRN | 1721163 |
NIST chemical information | (Dl) 2-aminopentanoic acid(760-78-1) |
EPA chemical information | Norvaline (760-78-1) |
Target
Human Endogenous Metabolite
In vitro studies
DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.