NSC 111656
4'-Bromo-3'-nitroacetophenone
CAS: 18640-58-9
Molecular Formula: C8H6BrNO3
NSC 111656 - Names and Identifiers
| Name | 4'-Bromo-3'-nitroacetophenone |
| Synonyms | NSC 111656 4-BROMO-3-NITROACETOPHENONE 3-Nitro-4-bromoacetophenone 4-Bromo-3-nitroacetophenone 4'-BROMO-3'-NITROACETOPHENONE 4'-Bromo-3'-nitroacetophenone Acetophenone, 4'-bromo-3'-nitro- 1-(4-bromo-3-nitrophenyl)ethanone 1-(4-BROMO-3-NITROPHENYL)ETHANONE 1-(4-BROMO-3-NITROPHENYL)ETHAN-1-ONE 1-(4-Bromo-3-nitrophenyl)-ethan-1-one |
| CAS | 18640-58-9 |
| EINECS | 242-469-6 |
| InChI | InChI=1/C8H6BrNO3/c1-5(11)6-2-3-7(9)8(4-6)10(12)13/h2-4H,1H3 |
| InChIKey | YFVOFFKNHQTQQE-UHFFFAOYSA-N |
NSC 111656 - Physico-chemical Properties
| Molecular Formula | C8H6BrNO3 |
| Molar Mass | 244.04 |
| Density | 1.637 |
| Melting Point | 117-121°C(lit.) |
| Boling Point | 275.4℃ |
| Flash Point | 120.4℃ |
| Vapor Presure | 0.00511mmHg at 25°C |
| Appearance | Amorphous Powder |
| Color | White to slightly yellow |
| BRN | 2050098 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6090 (estimate) |
NSC 111656 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29147000 |
NSC 111656 - Introduction
Nature:
4 '-Bromo-3'-nitroacetophenone is a yellow crystal with a pungent taste. It is a solid insoluble in water at normal temperature and soluble in organic solvents such as ethanol and dimethylformamide. The compound is highly toxic and should be handled and stored with care.
Use:
4 '-Bromo-3'-nitroacetophenone is useful as an intermediate in organic synthesis. It is commonly used in the preparation of other compounds, such as pesticides, dyes and pharmaceuticals. In addition, it can also be used as a research compound or analytical reagent.
Method:
The preparation of 4 '-Bromo-3'-nitroacetophenone is usually achieved by bromination of p-nitroacetophenone. One commonly used method is the reaction of nitroacetophenone with sodium bromide under acidic conditions. The reaction is usually carried out at room temperature, and appropriate safety measures are required to prevent leakage and contact of harmful substances.
Safety Information:
4 '-Bromo-3'-nitroacetophenone has certain toxicity and should be operated under strict experimental conditions. In case of contact with skin, eyes or respiratory tract, rinse immediately with plenty of water and seek medical help. During use, ensure good ventilation and wear appropriate personal protective equipment, such as gloves, glasses and protective clothing. In addition, the compound should be kept away from sources of ignition and strong oxidants, stored in closed containers, and avoid mixing with other chemicals. Please read carefully and follow the instructions on the safety data sheet when using.
Last Update：2024-04-09 20:52:54
