Name | 6-bromoisatin |
Synonyms | NSC 30748 AKOS B018432 6-Bromoisatin 6-BROMOISATIN 6-bromoisatin BROMOISATIN(6-) 6-Bromoindole-2,3-dione 6-BROMOINDOLE-2,3-DIONE 6-Bromo-2,3-Indolinedione 6-BROMOINDOLINE-2,3-DIONE 6-BROMO ISATINIC ANHYDRIDE 6-bromo-1H-indole-2,3-dione 6-BROMO-1H-INDOLE-2,3-DIONE 1H-Indole-2,3-dione,6-bromo- Indole-2,3-dione,6-bromo- (8CI) |
CAS | 6326-79-0 |
EINECS | 678-162-2 |
InChI | InChI=1/C8H4BrNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12) |
InChIKey | HVPQMLZLINVIHW-UHFFFAOYSA-N |
Molecular Formula | C8H4BrNO2 |
Molar Mass | 226.03 |
Density | 1.826±0.06 g/cm3(Predicted) |
Melting Point | 274°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Brown solid |
Color | Dark Yellow |
pKa | 8.83±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.649 |
MDL | MFCD01631138 |
Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
Hazard Class | IRRITANT |
Introduction | 6-bromoisatin is an indole diketone compound. Indolinedione is an effective anti-tumor component of traditional Chinese medicine indigo naturalis, and it is also the precursor of indirubin dimer, the leading compound of anticancer drugs. Indolinedione and its derivatives show good activity in anti-tumor, anti-virus, anti-bacteria and so on. |