NSC 350625

Name	TIC10
Synonyms	TIC10 TIC-10 TIC 10 CS-826 TIC10 TIC 10 NSC 350625 ONC201 ISOMER 7-benzyl-10-(2-Methylbenzyl)-2,6,7,8,9,10-hexahydroiMidazo[1,2-a]pyrido[4,3-d]pyriMidin-5(3H)-one 2,6,7,8,9,10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one
CAS	41276-02-2

Molecular Formula	C24H26N4O
Molar Mass	386.49
Solubility	DMSO: soluble2mg/mL, clear (warmed)
Color	white to beige
Storage Condition	2-8°C
In vitro study	TIC10 leads to an increase in TRAIL mRNA in a dose-dependent manner, inducing TRAIL protein localization on the cell surface of some tumor cell lines in a p53-independent manner. TIC10 has broad-spectrum activity against a variety of malignancies in vitro and induces increased sub-G1 DNA content, indicating that TRAIL-sensitive HCT116 p53
In vivo study	TIC10 and TRAIL handle HCT116 p53

Last Update：2024-01-02 23:10:35

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Product Name: TIC10 Visit Supplier Webpage Request for quotation
CAS: 41276-02-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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NSC 350625

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