Name | 4-Amino-6-chloropyrimidine |
Synonyms | NSC 42134 6-Chloropyrimidin-4-amine 6-chloropyrimidin-4-amine 6-Chloro-4-pyrimidinamine 4-Amino-6-chloropyrimidine 2-CHLORO-6-AMINOPYRIMIDINE 6-chloro-4-aminopyrimidine 4-AMINO-6-CHLOROPYRIMIDINE 6-CHLORO-PYRIMIDIN-4-YLAMINE 4-Pyrimidinamine, 6-chloro- (9CI) |
CAS | 5305-59-9 |
EINECS | 664-284-3 |
InChI | InChI=1/C4H4ClN3/c5-3-1-4(6)8-2-7-3/h1-2H,(H2,6,7,8) |
InChIKey | DUKKRSPKJMHASP-UHFFFAOYSA-N |
Molecular Formula | C4H4ClN3 |
Molar Mass | 129.55 |
Density | 1.437±0.06 g/cm3(Predicted) |
Melting Point | 215-216°C |
Boling Point | 289.0±20.0 °C(Predicted) |
Flash Point | 128.6°C |
Solubility | DMSO |
Vapor Presure | 0.00227mmHg at 25°C |
Appearance | Pale yellow solid |
Color | Pale Yellow |
pKa | 2.16±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.617 |
MDL | MFCD00053576 |
Physical and Chemical Properties | Appearance of pale yellow crystals melting point 215-216 ℃ |
Use | Pharmaceutical Intermediates |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 3 |
HS Code | 29335990 |
Hazard Note | Harmful |
Hazard Class | IRRITANT |
use | intermediate of sulfa-6-methoxine. |
production method | methyl cyanoacetate and methanol are added under acidic conditions to generate methyl 3-methoxy-3-iminopropionate, then amination to obtain acetamidamidine, and then cyclized with methanol and ethyl formate to prepare the product. |