NSC 54758

NSC 54758 - Names and Identifiers

Name	N-(benzyloxycarbonyl)-2-aminoacetonitrile
Synonyms	NSC 54758 N-CBZ-AMINOACETONITRILE N-Cbz-aminoacetonitrile benzyl (cyanomethyl)carbamate N-Carbobenzoxyaminoacetonitrile N-CARBOBENZOXYAMINOACETONITRILE Benzyl N-(cyanomethyl)carbamate N-(Carbobenzoxy)aminoacetonitrile N-(benzyloxycarbonyl)-2-aminoacetonitrile N-(BENZYLOXYCARBONYL)-2-AMINOACETONITRILE Benzyl Cyanomethylcarbamate N-Cbz-aminoacetonitrile Cyanomethylcarbamic Acid Benzyl Ester
CAS	3589-41-1
InChI	InChI=1/C10H10N2O2/c11-6-7-12-10(13)14-8-9-4-2-1-3-5-9/h1-5H,7-8H2,(H,12,13)

NSC 54758 - Physico-chemical Properties

Molecular Formula	C10H10N2O2
Molar Mass	190.2
Density	1.181g/cm³
Melting Point	61-63 °C (lit.)
Boling Point	376.4°C at 760 mmHg
Flash Point	181.5°C
Solubility	Chloroform (Sparingly), Methanol (Slightly)
Vapor Presure	7.24E-06mmHg at 25°C
Appearance	Solid
Color	Off-White
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.538
MDL	MFCD00033175

NSC 54758 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	36 - Wear suitable protective clothing.
UN IDs	3439
WGK Germany	3

NSC 54758 - Introduction

N-(benzyloxycarbonyl)-2-aminoacetonitrile, chemical formula C10H10N2O2, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: N-(benzyloxycarbonyl)-2-aminoacetonitrile is a colorless or light yellow solid.
2. Solubility: It can be dissolved in organic solvents (such as alcohols, ethers, disulfides, etc.).

Use:
1. synthetic intermediate: N-(benzyloxycarbonyl)-2-aminoacetonitrile is commonly used as an intermediate for the synthesis of other compounds, especially in the pharmaceutical field.
2. Drug synthesis: It can be used to synthesize biologically active compounds, such as drugs with anti-inflammatory, anti-tumor or antibacterial activities.

Preparation Method:
The preparation method of N-(benzyloxycarbonyl)-2-aminoacetonitrile is usually through the following steps:
1. Benzyl alcohol reacts with trichloroformic acid (CCl3COOH) to generate benzyloxycarbonylchloroformic acid (C6H5CH2OC(O)CCl2OH).
2. benzyloxycarbonyl chloroformic acid reacts with aminoacetonitrile (CH3CH(NH2)CN) under alkaline conditions to generate N-(benzyloxycarbonyl)-2-aminoacetonitrile.

Safety Information:
1. N-(benzyloxycarbonyl)-2-aminoacetonitril may be irritating to the eyes, skin and respiratory system. Appropriate personal protective measures should be taken, such as wearing protective glasses, protective gloves and respirators.
2. avoid contact with strong oxidants, avoid inhalation of dust, and avoid contact with fire sources.
3. in the operation should be carried out in a well ventilated place to avoid dust and steam.
4. In case of accidental contact, rinse the affected area immediately with plenty of water and seek medical help.
5. during storage, it should be sealed and kept in a dry, cool place, away from fire and incompatible substances.

Last Update：2024-04-09 15:17:57