O-(2-Fluoro-benzyl)-hydroxylamine hydrochloride
2-Fluoro-benzylhydroxylamine hydrochloride
CAS: 55418-27-4
Molecular Formula: C7H8FNO
O-(2-Fluoro-benzyl)-hydroxylamine hydrochloride - Names and Identifiers
O-(2-Fluoro-benzyl)-hydroxylamine hydrochloride - Physico-chemical Properties
| Molecular Formula | C7H8FNO |
| Molar Mass | 141.14 |
| Density | 1.176 |
| Boling Point | 238℃ |
| Flash Point | 98℃ |
| Physical and Chemical Properties | Appearance: white or yellowish crystals Melting Point: 179-182 ℃ soluble in hot water, soluble in alcohol, insoluble in ether, chloroform and toluene, etc. The solution is acidic. |
| Use | It is used as an intermediate in the production of pharmaceuticals, pesticides and antibacterial agents. |
O-(2-Fluoro-benzyl)-hydroxylamine hydrochloride - Introduction
hydrochloride (hydrochloride) is an organic compound. It has the formula C7H8FNO · HCl and a molecular weight of 187.59g/mol.
The following is a brief description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in water, soluble in alcohol and ketone solvents
-Melting point: about 170-173°C
Use:
The hydrochloride has the following main uses:
-as an intermediate in organic synthesis, participate in the synthesis of ketones, esters and aldehydes
-for hydrogenation, reduction and alkylation reactions in organic synthesis
Preparation Method:
A hydrochloride is generally synthesized by the following steps:
1. o-fluorobenzyl bromide reacts with hydroxyl amine under alkaline conditions to give o-fluorobenzyl oximine.
2. o-fluorobenzoxylamine reacts with hydrochloric acid to prepare hydrochloride.
Safety Information:
-a hydrochloride is an organic compound, when used to follow the general laboratory safety procedures.
-Avoid direct contact with skin and eyes during operation. For accidental contact, flush the affected area immediately with plenty of water and seek medical help.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-When using and handling this compound, properly dispose of waste and comply with local regulations.
The following is a brief description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in water, soluble in alcohol and ketone solvents
-Melting point: about 170-173°C
Use:
The hydrochloride has the following main uses:
-as an intermediate in organic synthesis, participate in the synthesis of ketones, esters and aldehydes
-for hydrogenation, reduction and alkylation reactions in organic synthesis
Preparation Method:
A hydrochloride is generally synthesized by the following steps:
1. o-fluorobenzyl bromide reacts with hydroxyl amine under alkaline conditions to give o-fluorobenzyl oximine.
2. o-fluorobenzoxylamine reacts with hydrochloric acid to prepare hydrochloride.
Safety Information:
-a hydrochloride is an organic compound, when used to follow the general laboratory safety procedures.
-Avoid direct contact with skin and eyes during operation. For accidental contact, flush the affected area immediately with plenty of water and seek medical help.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-When using and handling this compound, properly dispose of waste and comply with local regulations.
Last Update：2024-04-10 22:29:15
