O6-METHYL-2'-DEOXYGUANOSINE

O6-METHYL-2'-DEOXYGUANOSINE - Names and Identifiers

Name	O6-METHYL-2'-DEOXYGUANOSINE
Synonyms	O6-METHYL-2'-DEOXYGUANOSINE 2-Amino-6-methoxy-2'-deoxy-6-deaminoadenosine 9-(2-Deoxy-β-D-ribofuranosyl)-6-methoxy-9H-purin-2-amine 2-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methoxypurine (2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol (2R,3S,5R)-5-(2-amino-6-methoxy-purin-9-yl)-2-methylol-tetrahydrofuran-3-ol
CAS	964-21-6

O6-METHYL-2'-DEOXYGUANOSINE - Physico-chemical Properties

Molecular Formula	C11H15N5O4
Molar Mass	281.27
Melting Point	109 - 115°C
Solubility	Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
Storage Condition	2-8°C

O6-METHYL-2'-DEOXYGUANOSINE - Upstream Downstream Industry

Raw Materials

ZPBYVFQJHWLTFB-UHFFFAOYSA-N
7-METHYLGUANINE
Methyl methanesulfonate

O6-METHYL-2'-DEOXYGUANOSINE - Introduction

O6-METHYL-2 '-DEOXYGUANOSINE(O6-METHYL-2'-DEOXYGUANOSINE) is an organic compound with the chemical formula C11H15N5O4.

Properties: O6-METHYL-2 '-DEOXYGUANOSINE is a white crystalline powder, soluble in water and some organic solvents. It has a certain chemical stability, but it will decompose under strong acid or strong alkali conditions.

use: O6-METHYL-2 '-DEOXYGUANOSINE has a certain importance in the field of medicine. It can be used as a substrate for the DNA repair process. In cells, O6-METHYL-2 '-DEOXYGUANOSINE can react with damaged sites in DNA (such as methylation sites caused by chemicals or radiation) and through the action of repair enzymes, the methyl group is removed from the DNA, thereby maintaining the integrity of the DNA.

preparation method: O6-METHYL-2 '-DEOXYGUANOSINE preparation method is varied, the commonly used method is the use of enzyme reaction or chemical synthesis. The enzymatic method usually uses a random hydroxymethylating enzyme (hydroxymethylating enzyme) to catalyze the methylation reaction of 2 '-deoxyguanosine.

Safety information: Because the O6-METHYL-2 '-DEOXYGUANOSINE plays an important role in cells, it has low toxicity. In general, it is a relatively safe compound. However, it is still necessary to follow general laboratory safety practices, maintain a well-ventilated operating environment, and avoid direct contact with eyes and skin. In addition, the compound should be stored and handled carefully to avoid contact with inappropriate chemicals or conditions to prevent accidents.

Last Update：2024-04-09 21:04:16