ODS - Names and Identifiers
ODS - Introduction
ODS is a commonly used stationary phase, all called Octadecyl Silane. It mainly refers to the longer carbon chain (octadecane) alkyl silane, with silica gel or other matrix fixed in the liquid chromatography column.
Nature of ODS:
1. Highly hydrophobic: Eighteen carbon chains make ODS have low solubility in polar solvents.
2. High surface area: ODS has a large inner pore structure, which helps to enhance the adsorption and retention capacity of the sample.
3. Stability: ODS has good chemical stability under neutral and acidic conditions, but is susceptible to hydrolysis damage under alkaline conditions.
Uses of ODS:
1. Liquid chromatography separation: ODS is widely used in liquid chromatography analysis, especially for the separation and analysis of polar compounds.
2. Pharmaceutical Analysis: ODS can be used for qualitative and quantitative analysis of pharmaceutical ingredients.
3. Environmental analysis: ODS can be used for the separation and determination of organic matter in environmental samples, such as organic pollutants in water.
Preparation of ODS:
The preparation of ODS is usually obtained by reacting an alkylsilane compound with the surface of silica gel. The specific preparation method can be adjusted and optimized according to different experimental requirements.
Security information for
ODS:
1. ODS are susceptible to moisture and need to be stored in a dry environment.
2. ODS is sensitive to flame and high temperature and should be kept away from open flame and high temperature.
3. Avoid skin contact and inhalation when using ODS to avoid dust.
4. Use the process should wear personal protective equipment, such as laboratory gloves and safety glasses.
Last Update：2024-04-09 02:00:51