ONO-LB 457
ONO-LB 457
CAS: 134578-96-4
Molecular Formula: C27H34O7
ONO-LB 457 - Names and Identifiers
| Name | ONO-LB 457 |
| Synonyms | ONO-4057 ONO-LB 457 Benzenepropanoic acid, 2-(4-carboxybutoxy)-6-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]- |
| CAS | 134578-96-4 |
ONO-LB 457 - Physico-chemical Properties
| Molecular Formula | C27H34O7 |
| Molar Mass | 470.55 |
| Density | 1.173±0.06 g/cm3(Predicted) |
| Boling Point | 704.8±60.0 °C(Predicted) |
| pKa | 4.68±0.10(Predicted) |
| Storage Condition | Room Temprature |
| In vivo study | Mean animal survivals of the ONO4057-treated animals significantly prolong to 21.0±4.4 days compare with 12.0±0.6 days in control group. Histological findings from grafts taken on day 7 show that severe focal cellular infiltration is observed in both groups, but the degree of hepatocyte necrosis in ONO4057-treated anmimals is milder than that in control group. |
ONO-LB 457 - References
| biological activity | ONO4057 is an antagonist of the leucotriene B4 receptor with an IC50 value of 0.7±0.3 μm. |
Last Update：2024-04-09 20:49:11
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