Molecular Formula | C82H114N20O17S |
Molar Mass | 1683.97 |
Density | 1.338±0.06 g/cm3(Predicted) |
Boling Point | 1995.8±65.0 °C(Predicted) |
Water Solubility | Soluble in water at 1mg/ml |
Solubility | H2O: 1 mg/mL, clear, colorless |
pKa | 3.07±0.10(Predicted) |
Storage Condition | −20°C |
Physical and Chemical Properties | Biologically active alpha-factor binding veromone, East is a tri-peptide that is secreted by the alpha cells of S. Cereal, acting through the Ste2p receptor. |
In vitro study | α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35 S-α-factor to haploid a cells, with K d of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
Target
Ste2p
in vitro studies
α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35 S-α-factor to haploid a cells, with K d of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability.
biological activity | alpha-Factor Mating Pheromone, east is a thirteen peptide, which is secreted by alpha cells of S. cerevisiae and acts through the Ste2p receptor. |
target | step 2p |
in vitro research | alpha-Factor Mating Pheromone, yeast is synthesized constitutively by MAT α cells and acting on MATA cells. α-Factor Mating Pheromone, Yeast inhibits the division cycle of east a cells, and competes for binding of 35 S-α-factor to haploid a cells, with K d of 0.3 μ m, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, east binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability. |