POWDER LGD-4033 LIGANDROL

POWDER LGD-4033 LIGANDROL - Names and Identifiers

Name	LGD-4033
Synonyms	LGD4033 LGD-4033 LIGANDROL POWDER LGD-4033 LIGANDROL LIGANDROL (LGD-4033, VK-5211) lgd 4033 sarms powder lgd-4033 ligandrol 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile 4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile(LGD-4033)
CAS	1165910-22-4
EINECS	1806241-263-5

POWDER LGD-4033 LIGANDROL - Physico-chemical Properties

Molecular Formula	C14H12F6N2O
Molar Mass	338.25
Density	1.45±0.1 g/cm3(Predicted)
Melting Point	108 - 111°C
Boling Point	439.9±45.0 °C(Predicted)
Solubility	Acetone (Slightly), Chloroform (Slightly, Heated), Methanol (Slightly)
Appearance	A crystalline solid
Color	White to Pale Beige
pKa	12.06±0.20(Predicted)
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic
Physical and Chemical Properties	Bioactive Ligandrol (LGD-4033, VK-5211) is a novel, non-steroidal, orally selective modulator of the androgen receptor with high affinity (Kd of about 1 nM) and high selectivity for the androgen receptor.
Use	Use LGD-4033 is a non-steroidal oral, selective androgen receptor modulator in healthy young adults
In vivo study	In animal models, LGD-4033 have anabolic activity in muscle, absorption and anabolic activity in bone, and selectivity in muscle is higher than in prostate. At the concentrations tested, LGD-4033 was safe and well tolerated, with a long elimination half-life of about 24-36 hours and a linear pharmacokinetic profile.

POWDER LGD-4033 LIGANDROL - Introduction

LGD-4033 is an organic compound whose Properties, Uses, methods and safety information are as follows:

Nature:
-Appearance: Colorless solid
-Molecular formula: C13H8F6N2O
-Molecular weight: 338.21g/mol
-Melting point: 130-132 ° C
-Boiling point: 370 ° C
-Solubility: Insoluble in water, soluble in organic solvents

Use:
- LGD-4033 is a chiral compound, which is often used in asymmetric catalytic reactions in the synthesis of chiral drugs.
-It can also be used as an important intermediate in organic synthesis and participate in various organic synthesis reactions.

Preparation Method:
The preparation method of LGD-4033 is relatively complicated and usually needs to be carried out in the organic synthesis laboratory or industrial production. The preparation method can be designed and optimized according to specific chemical research needs.

Safety Information:

Last Update：2024-04-09 01:59:58