Paris II
Polyphyllin II
CAS: 50773-42-7
Molecular Formula: C51H82O20
Paris II - Names and Identifiers
Paris II - Physico-chemical Properties
| Molecular Formula | C51H82O20 |
| Molar Mass | 1015.2 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Melting Point | 222～231℃ |
| Specific Rotation(α) | []15D 100 (c, 1 in Py). []D 113.4 (c, 0.57 in MeOH) |
| Solubility | Soluble in methanol, DMSO and other solvents, insoluble in petroleum ether, etc. |
| Appearance | White powder |
| pKa | 12?+-.0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Sensitive to light |
| MDL | MFCD16294847 |
| Physical and Chemical Properties | It is soluble in methanol, ethanol, DMSO and other organic solvents, and is derived from the extract of Achexinus chinensis. |
Paris II - Reference
| Reference Show more | 1. Liu Jia, Yang Yali, Zhang Peng, et al. Analysis of the content of saponins in different parts of 4 kinds of Paris polyphylla [J]. Chinese Journal of Experimental formulology, 2016, Vol. 22, 16, pages 44-48. 2. Wang Haiming, et al. Determination of four saponins in Rhizoma Paridis by HPLC [J]. Journal of Dalian Minzu University, 2018, 20(001):17-20. 3. Ye Feifei, Xu Haobo, Wang Chunxia, et al. Simultaneous determination and cluster analysis of four saponins from Paris polyphylla [J]. Chinese patent medicine 2016 38(11):2413-2413. 4. Liu Jia, Zhang Peng, Song Fa-Jun, etc. Analysis of the content of four kinds of saponins in the ground part of Paris polyphylla [J]. Shi Zhen, National Medicine, 2015, 026(005):1233-1235. 5. Liu Xiaofen, Huang Xiaozhi, Wang Heshan. Quality Evaluation and Analysis of cultivated Paridis in Fujian province [J]. Fujian Traditional Chinese Medicine, 2012, 43(005):53-55. 6. Liu Xiaofen, Yang Chengzi, Huang Zehao, etc. Characteristics of Rhizoma Paridis and content analysis of four saponins [J]. Fujian traditional Chinese medicine, 2014, 045(001):53-56. 7. Wang Shibao, Cai Yanni, Jia Huimei et al. Determination of seven steroidal saponins in Rhizoma Paridis from different sources by HPLC [J]. Northwest Pharmaceutical Journal, 2017, 32(002):133-138. 8. Wang Shibao, Su Ying, Li Huining et al. Optimization of reflux extraction of steroidal saponins from Rhizoma Paridis by response surface methodology [J]. Shaanxi Agricultural Sciences 2019 065(001):46-52. 9. Ma Jingqian, Cui Naiyan, Yu River, Li Zheng, Liu Erwei, Bisong Tao. Evaluation of effects of drying methods on effective components of Dioscorea composita based on quantitative analysis of four saponins [J]. Central South pharmacy, 2021,19(03):413-418. 10. Liu, Feng, et al. "Comparative analysis of proteinic and metabolic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https:// doi.org/10.1016/j. Jprot.23/2019 11. Liu, Feng, et al. "Comparative analysis of proteomic and metabolomic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https://doi.org/10.1016/j.jprot.2019.02.003 12. [IF=4.072] Yan Yin et al."A cytochrome P450 monooxygenase responsible for the C- 22 hydroxylation step in the Paris polyphylla steroidal saponin biosynthesis pathway."Phytochemistry. 2018 Dec;156:116 13. [IF=4.044] Feng Liu et al."Comparative analysis of proteomic and metabolomic profiles of different species of Paris."J Proteomics. 2019 May;200:11 14. [IF=5.645] Bo Li et al."Organ-specific transcriptome sequencing and mining of genes involved in polyphyllin biosynthesis in Paris polyphylla."Ind Crop Prod. 2020 Nov;156:112775 15. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992 16. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724 |
Paris II - Reference Information
| biological activity | Polyphyllin B (Formosanin C, FC) is a diosgenin isolated from Paris formosana, it is also an immunomodulator with anti-tumor activity. Polyphyllin B (Formosanin C, FC) can induce apoptosis. |
| Use | hemostasis, expectorant and antibacterial, sedative and analgesic, antiearly pregnancy sperm killing, anti-cytotoxicity. for content determination/identification/pharmacological experiments. Pharmacological effects: anti-inflammatory, anti-tumor, anti-virus, lower cholesterol, lower blood pressure and other effects. |
Last Update：2024-04-09 15:16:55
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Product Name: Polyphyllin II Visit Supplier Webpage Request for quotationCAS: 50773-42-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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