Phenethylzinc bromide - Names and Identifiers
Phenethylzinc bromide - Physico-chemical Properties
Molecular Formula | C8H9BrZn
|
Molar Mass | 250.45 |
Density | 0.965g/mLat 25°C |
Boling Point | 65°C |
Flash Point | 1°F |
Water Solubility | Reacts with water. |
Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
Storage Condition | 2-8°C |
Sensitive | Air Sensitive |
Phenethylzinc bromide - Risk and Safety
Risk Codes | R14 - Reacts violently with water
R19 - May form explosive peroxides
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin.
R40 - Limited evidence of a carcinogenic effect
R36/37 - Irritating to eyes and respiratory system.
R11 - Highly Flammable
|
Safety Description | S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S33 - Take precautionary measures against static discharges.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
|
UN IDs | UN 2056 3/PG 2 |
WGK Germany | 1 |
Hazard Class | 4.3 |
Phenethylzinc bromide - Introduction
Phenethylzinc bromide is an organic zinc compound with the chemical formula C8H9BrZn. It is a colorless liquid, unstable at room temperature, susceptible to moisture and oxygen in the air, and will undergo decomposition reactions.
Phenethylzinc bromide are commonly used as reagents in organic synthesis. It can be used as a reagent in organic synthesis, especially as a substitute for Grignard reagents (Grignard reagents). Its main purpose is to carry out carbon-carbon bond formation reactions, usually with halogenated hydrocarbons or acyl halides to generate new carbon-carbon bonds. Such reagents can be used in the synthesis of pharmaceuticals, fragrances and other organic compounds.
The preparation of Phenethylzinc bromide usually adopts Grignard reagent method. The ethyl bromide is dissolved in anhydrous ether, then zinc dust is added and the reaction mixture is stirred under an inert atmosphere such as nitrogen. After completion of the reaction, the product is isolated to give the Phenethylzinc bromide.
Because Phenethylzinc bromide is an organic zinc compound, it needs to pay attention to safety matters during use. The main safety precautions include avoiding contact with air, moisture and oxygen to prevent their decomposition reactions. In addition, Phenethylzinc bromide are irritating and corrosive to the skin, eyes and respiratory system, wear appropriate protective equipment and maintain a well-ventilated working environment. When handling and storing Phenethylzinc bromide, follow proper laboratory practices and follow relevant safety guidelines and recommendations.
Last Update:2024-04-09 20:52:54