Phenol Red, sodium salt
Phenol Red sodium salt
CAS: 34487-61-1
Molecular Formula: C19H13NaO5S
Phenol Red, sodium salt - Names and Identifiers
| Name | Phenol Red sodium salt |
| Synonyms | SODIUM PHENOL RED PHENOLSULFONPHTHALEIN Phenol Red sodium salt Phenol Red, sodium salt PHENOL RED, WATER SOLUBLE PHENOLSULFONPHTHALEIN NA-SALT PHENOLSULFONPHTHALEIN, SODIUM SALT PHENOLSULFONEPHTHALEIN SODIUM SALT PHENOLSULPHONEPHTHALEIN SODIUM SALT PHENOLSULFONEPHTHALEIN MONOSODIUM SALT sodium 4-[3-(4-hydroxyphenyl)-1,1-dioxido-3H-2,1-benzoxathiol-3-yl]phenolate sodium 2-[(4-hydroxyphenyl)(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate |
| CAS | 34487-61-1 |
| EINECS | 252-057-8 |
| InChI | InChI=1/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24/h1-12,20H,(H,22,23,24)/p-1 |
Phenol Red, sodium salt - Physico-chemical Properties
| Molecular Formula | C19H13NaO5S |
| Molar Mass | 376.36 |
| Density | 0.972 |
| Melting Point | 285°C (dec.)(lit.) |
| Boling Point | 285 °C |
| Water Solubility | soluble |
| Solubility | Soluble in water yielding a dark red solution (25 mg/ml), alcohol (4 mg/ml), methanol |
| Appearance | Shiny Powder |
| Color | White |
| Odor | Odorless |
| Maximum wavelength(λmax) | ['423nm, 557nm'] |
| Merck | 14,7247 |
| BRN | 6260026 |
| pKa | 7.69, 7.9, 1.3(at 25℃) |
| Storage Condition | room temp |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| MDL | MFCD00066901 |
| Use | Used as acid-base indicator |
| In vitro study | Phenol Red sodium salt is commonly employed as a cell tissue culture pH marker. Under normal conditions, phenol red added to the growth medium will have a pink-red color. Dying cells or overgrowth of contaminants will cause a change in pH resulting in a change in indicator color. Phenol red bears a structural resemblance to some nonsteroidal estrogens and has significant estrogenic activity at the concentrations (15-45 μM) at which it is found in tissue culture media. Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells and stimulates the proliferation of estrogen receptor-positive MCF-7 breast cancer cells in a dose-dependent manner but has no effect on the growth of estrogen receptor-negative MDA-MB-231 breast cancer cells. Phenol red is a simple, rapid and inexpensive method for the measurement of hydrogen peroxide produced by cells in culture. The assay is based on the horseradish peroxidase-mediated oxidation of phenol red by hydrogen peroxide which results in the formation of a compound demonstrating increased absorbance at 610 nm. |
Phenol Red, sodium salt - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29349990 |
Phenol Red, sodium salt - Reference Information
| pH indicator color change ph range | yellow (6.8) to red (8.4) |
| main applications | Sensor, optical devices, paints, sterilization process, fertilizer, detecting viable cells, gastrointestinal mcosa, antibacterial agent, drugs, pharmacology |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Biological activity | Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is commonly used as a pH indicator in tissue culture groups, ranging from 6.8 (yellow) to 8.2 (red). Phenol Red sodium salt can bind to the estrogen receptor of MCF-7 human breast cancer cells. |
| Target | Value |
| use | as acid-base indicator |
Last Update：2024-04-10 22:29:15
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