Phenylzinc bromide
Phenylzinc bromide
CAS: 38111-44-3
Molecular Formula: C6H5BrZn
Phenylzinc bromide - Names and Identifiers
Phenylzinc bromide - Physico-chemical Properties
| Molecular Formula | C6H5BrZn |
| Molar Mass | 222.4 |
| Density | 0.99g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
Phenylzinc bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R37 - Irritating to the respiratory system |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
Phenylzinc bromide - Introduction
Phenylzinc bromide is an organic compound with the chemical formula C6H5ZnBr. It is a white solid that is stable in air but decomposes when exposed to water. Its use is mainly as an important ligand and reagent in organic synthesis.
Phenylzinc bromide can be used in the synthesis of Grignard reagents and metal organic chemical reactions. It can be used as a nucleophile in C- C coupling reactions. Various organic compounds such as ketones, alcohols, acids and the like can be synthesized by reaction with halogenated hydrocarbons, aldehydes, ketones and the like.
The preparation method of Phenylzinc bromide is generally obtained by the reaction of zinc and phenyl magnesium bromide (Phenylmagnesium bromide). Zinc and phenylmagnesium bromide were first suspended in an anhydrous environment and reacted at room temperature for several hours. After completion of the reaction, the solution was treated with an acid to neutralize the excess organomagnesium reagent, followed by filtration to obtain a Phenylzinc bromide.
in the process of using Phenylzinc bromide need to pay attention to safety. It may cause irritation to the skin, eyes and respiratory tract, so it is necessary to wear appropriate protective equipment, such as laboratory gloves, protective glasses and protective masks. In addition, Phenylzinc bromide should be kept away from fire sources and stored in a dry, well-ventilated place to avoid contact with oxidants and water. Observe local environmental regulations when disposing of waste.
Phenylzinc bromide can be used in the synthesis of Grignard reagents and metal organic chemical reactions. It can be used as a nucleophile in C- C coupling reactions. Various organic compounds such as ketones, alcohols, acids and the like can be synthesized by reaction with halogenated hydrocarbons, aldehydes, ketones and the like.
The preparation method of Phenylzinc bromide is generally obtained by the reaction of zinc and phenyl magnesium bromide (Phenylmagnesium bromide). Zinc and phenylmagnesium bromide were first suspended in an anhydrous environment and reacted at room temperature for several hours. After completion of the reaction, the solution was treated with an acid to neutralize the excess organomagnesium reagent, followed by filtration to obtain a Phenylzinc bromide.
in the process of using Phenylzinc bromide need to pay attention to safety. It may cause irritation to the skin, eyes and respiratory tract, so it is necessary to wear appropriate protective equipment, such as laboratory gloves, protective glasses and protective masks. In addition, Phenylzinc bromide should be kept away from fire sources and stored in a dry, well-ventilated place to avoid contact with oxidants and water. Observe local environmental regulations when disposing of waste.
Last Update：2024-04-10 22:29:15
