Phosphinic acid
Hypophosphorous acid
CAS: 6303-21-5
Molecular Formula: HO2P
Phosphinic acid - Names and Identifiers
| Name | Hypophosphorous acid |
| Synonyms | HPA Phosphinic acid phosphinic acid hypophosphorous phosphenous acid Hypophosphite Acid Hypophosphorous acid hydroxy(oxo)phosphonium Hypophosphorousacidcolorlessliq hypophosphorousacid(corrosiveliquid,acidic,inorganic,n.o.s.) |
| CAS | 6303-21-5 |
| EINECS | 228-601-5 |
| InChI | InChI=1/H3O2P/c1-3-2/h3H2,(H,1,2) |
| InChIKey | GQZXNSPRSGFJLY-UHFFFAOYSA-N |
Phosphinic acid - Physico-chemical Properties
| Molecular Formula | HO2P |
| Molar Mass | 63.980501 |
| Density | 1.206g/mLat 20°C(lit.) |
| Melting Point | -25 °C |
| Boling Point | 108 °C (759.8513 mmHg) |
| Water Solubility | SOLUBLE |
| Vapor Presure | <17 mmHg ( 20 °C) |
| Appearance | hygroscopic crystals or colorless oily liquid |
| Color | Colorless |
| Merck | 13,4894 |
| pKa | pK1 1.1. |
| Storage Condition | no restrictions. |
| Stability | Stable. Incompatible with strong bases. Reacts violently with oxidizing agents, strong bases, mercury (II) nitrate and mercury (II) oxide. Do not heat above 100 C. |
| Physical and Chemical Properties | Colorless oily liquid or deliquescent crystal. Soluble in hot water, ethanol, ether. Soluble in cold water. |
| Use | Is a strong reducing agent, used in the preparation of sodium hypophosphite, calcium hypophosphite and other secondary phosphate |
Phosphinic acid - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3264 8/PG 3 |
| WGK Germany | 1 |
| RTECS | SZ6400000 |
| TSCA | Yes |
| HS Code | 28111990 |
| Hazard Class | 8 |
| Packing Group | II |
Phosphinic acid - Reference Information
| Update Date: | 2022/11/12 10:05:38 |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | hypophosphorous acid, also known as "hypophosphorous acid", colorless oily or deliquescent crystal, is an important product of fine chemicals. The main use is as a reducing agent for electroless plating, to prevent the color change of phosphoric acid resin, can also be used for esterification reaction catalyst, refrigerant, especially for the production of high purity sodium hypophosphite. There are many preparation methods, among which the common preparation methods in industry are ion exchange resin method and electrodialysis method. |
| properties | colorless oily or deliquescent crystals. Melting Point: 26.5 °c. Relative density (specific gravity):1.439 (solid, 19 °c). Soluble in water, ethanol and ether, and with water, ethanol, acetone can be mixed in any ratio. In the air, it is easy to deliquescence to slurry liquid, and the aqueous solution is acidic. Hypophosphorous acid is a monoacid, in aqueous solution, hypophosphorous acid is a strong acid, Ka = 10-2(25 ° C); Relatively stable at room temperature; 130 ° C disproportionation reaction, decomposition of phosphine and phosphorous acid: has a strong reduction, can make the heavy metal salt solution reduced to metal, such as Cu2 ,Hg2 ,Ag, such as: weak oxidant, encounter strong reducing agent itself is reduced to phosphine, phosphine. |
| preparation method | 1. The phosphorus and barium hydroxide solution is heated to generate its barium salt Ba(H2PO2)2 · 2H2O. Sulfuric acid is added to the barium hypophosphite solution to precipitate Ba2: hypophosphorous acid can be obtained by evaporation under reduced pressure and crystallization at low temperature. In this method, due to the solubility of barium salt is small, the concentration of hypophosphorous acid is not high, and the industrial products are more recrystallized and purified. 2. Barium hypophosphite (or calcium) is obtained by co-heating barium oxide (or lime) solution with white phosphorus, then interacting with sulfuric acid, filtering and concentrating, alternatively, the sodium hypophosphite solution may be obtained by treatment with an H-type ion exchange resin. This method requires a large amount of resin, and the regeneration and cleaning steps of the resin are cumbersome, making it generally more than $7 per pound. It is only suitable for small batch production and cannot be applied on a large scale. 3. Hypophosphorous acid was prepared by electrodialysis, in which the electrodialysis cell was divided into three parts: anode chamber, raw material chamber and cathode chamber, separated by anion membrane and cation membrane, sodium hypophosphite solution (concentration 100g/L ~ 500g/L) is placed between the two membranes. The positive electrode chamber is 5g/L of dilute hypophosphorous acid, and the negative electrode chamber is dilute sodium hydroxide solution (5g/L), after passing direct current between the two electrodes (3V ~ 36V), the positive electrode releases oxygen to generate hypophosphorous acid; The negative electrode releases hydrogen to generate by-product sodium hydroxide, and the reaction time is 3~21H. The reactions of the positive electrode chamber and the negative electrode chamber are respectively as follows: the method of obtaining hypophosphorous acid by electrodialysis is simple and the equipment investment is small and suitable for large-scale production. 4. Starting from the industrial grade sodium hypophosphite, the anions such as Cl-and SO42-, which have great influence on the quality index of hypophosphorous acid, are removed by precipitation, and the heavy metal ions are removed from the solution by forming sulfide precipitation, then the hypophosphorous acid was prepared by using strong acid cation exchange resin to remove sodium, and high purity grade products were obtained. The method for preparing high-grade hypophosphorous acid is technically feasible, simple in process, convenient in operation and good in product quality, and can meet the needs of high-tech fields such as electronic industry and national defense industry. The process flow of the process is: |
| Use | 1. As a reducing agent for electroless plating; 2. For preventing the discoloration of phosphoric acid resin; 3. As a catalyst for esterification, refrigerant; 4. For the preparation of hypophosphite, its sodium salt, manganese salt, iron salt and so on are usually used as tonic drugs; 5. Used in medicine and as reducing agent, determination of arsenic, tellurium and separation of tantalum, niobium and other reagents. is a strong reducing agent for the preparation of sodium hypophosphite, hypophosphite and other secondary phosphates used in an electroplating bath. Pharmaceutical. Reducing agent. General reagents. is a strong reducing agent, used in the preparation of sodium hypophosphite, calcium hypophosphite and other secondary phosphate This product is widely used as a reducing agent, can be Ag, Cu, Ni, Hg and other metals reduced to the corresponding metal, used As test As, Nb, Ta and other reagents, can also be used for the preparation of Na, K, Ca, Mn, Fe and other kinds of hypophosphite (1) As alkyd resin antioxidant color reducing agent. (2) used as a reducing agent. (3) the preparation of hypophosphite salts, such as sodium hypophosphite, calcium hypophosphite, manganese hypophosphite, iron hypophosphite and so on. |
| toxicity | non-flammable. However, contact with the H porogen may cause combustion. When the oxidant is intense reaction and combustion. By high heat decomposition of highly toxic phosphine gas, and even explosion. Corrosive. Hypophosphorous acid is often added to a refreshing drink because it is not absorbed. So the risk is small, but especially concentrated hypophosphite will harm the gastrointestinal tract. Accidentally splash into the eyes or skin contact with a large amount of water to rinse. Production operators should wear protective clothing and other labor protection products. The production equipment is closed and the workshop is well ventilated. |
| production method | ion exchange resin method approximately 70g of cation exchange resin moistened with water was packed into a glass tube, with 5 mol/L hydrochloric acid circulation about 15min, after sufficient water washing, the high purity sodium hypophosphite aqueous solution (15g/60 ml H2O) flow through, resin column with 50 ml, this was then rinsed with 25 rnl of distilled water. The effluent acid and washings were combined and concentrated by evaporation on a water bath. The concentrated acid was dehydrated in a high vacuum desiccator with P205, cooled to crystallize, filtered, and recrystallized to obtain the final hypophosphorous acid. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:52
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